Patterns of left ventricular hypertrophy in essential hypertension: Should echocardiography guide the pharmacological treatment?

Padrão de remodelação e função ventricular em ratos expostos à fumaça do cigarro

“…Considering the presence of one of the four different remodeling patterns, an aspect that is worthy of note is that the same phenomenon was observed in clinical studies, in arterial hypertension models 7,17 . In the case of arterial hypertension, although the mechanisms are not completely clear, the different geometry patterns are explained by the different physiopathological mechanisms for hypertension, with different hemodynamic patterns.…”

“…In the case of arterial hypertension, although the mechanisms are not completely clear, the different geometry patterns are explained by the different physiopathological mechanisms for hypertension, with different hemodynamic patterns. Hence, the geometry would depend on the vasoconstriction degree, the intensity of activation of neurohumoral factors and the presence of volume overcharge 17 . In our study, however, the animals exposed to cigarette smoke present the same characteristics.…”

Relevância do padrão de remodelamento ventricular no modelo de infarto do miocárdio em ratos

“…Thus, the geometry would depend on the degree of vasoconstriction, the intensity of activation of neurohumoral factors and the presence of volume overload 12 …”

The Progression of Hypertensive Heart Disease

“…Differences in plasma renin activity are widespread in hypertensive subjects, 45,46 and some investigators equate high-versus low-renin states with concentric versus eccentric hypertrophy, respectively. 47 Patients with eccentric hypertrophy have been shown to have low plasma renin activity. 48 Other neurohormones, including angiotensin II and aldosterone, have also been associated with LV geometry in small cross-sectional studies.…”