Pb exposure causes non-linear accumulation of Pb in D. melanogaster controlled by metallothionein B and exerts ecological effects

Li, Ying; Tian, Xuemin; Zang, Xiya; Yang, Shuyu; Qiao, Hui; Zhu, Chunmei; Moussian, Bernard; Wang, Yiwen

doi:10.1016/j.scitotenv.2023.165680

Cited by 6 publications

(1 citation statement)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Once inside the cell, lead can be expelled by ATPase efflux pumps, such as ZntA and CadA (Newsome & Falagán, 2021), or by proteins encoded by the pbr resistance operon (Wei et al, 2014). Intracellular and periplasmic accumulation of Pb through metallothioneins was also observed (Yu et al, 2023). Alternatively, strategies based on the reduction of its mobility by precipitation with phosphate or oxalic acid (Liang et al, 2016;Sharma et al, 2018) or through siderophores (Liu et al, 2023) have been also described.…”

Section: Bacterial Detoxification Of Other Metalsmentioning

confidence: 99%

Bacterial tolerance and detoxification of cyanide, arsenic and heavy metals: Holistic approaches applied to bioremediation of industrial complex wastes

Olaya‐Abril,

Biełło,

Rodríguez‐Caballero

et al. 2024

Microbial Biotechnology

View full text Add to dashboard Cite

Cyanide is a highly toxic compound that is found in wastewaters generated from different industrial activities, such as mining or jewellery. These residues usually contain high concentrations of other toxic pollutants like arsenic and heavy metals that may form different complexes with cyanide. To develop bioremediation strategies, it is necessary to know the metabolic processes involved in the tolerance and detoxification of these pollutants, but most of the current studies are focused on the characterization of the microbial responses to each one of these environmental hazards individually, and the effect of co‐contaminated wastes on microbial metabolism has been hardly addressed. This work summarizes the main strategies developed by bacteria to alleviate the effects of cyanide, arsenic and heavy metals, analysing interactions among these toxic chemicals. Additionally, it is discussed the role of systems biology and synthetic biology as tools for the development of bioremediation strategies of complex industrial wastes and co‐contaminated sites, emphasizing the importance and progress derived from meta‐omic studies.

show abstract