PCF with immobilized silver nanoparticles as an optofluidic SERS sensing platform

Han, Yun; Tan, Siliu; Oo, Maung Kyaw Khaing; Du, Henry

doi:10.1117/12.848584

Cited by 2 publications

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“…SERS measurements were conducted using a custom-build Raman spectrometer 14 Raman shift (cm') end for Raman excitation was between 4.5 to 5 mW. All SERS spectra were acquired for 20 s and data were processed using Origin 8.0 software.…”

Section: Sers Measurementsmentioning

confidence: 99%

“…The potential of SERS for biosensing with high specificity has been demonstrated and broadly explored [6][7][8] . SERS is a surface-sensitive technique that enhances Raman scattering by molecules adsorbed on surfaces of metal (mainly Ag, Au and Cu) nanostructure and the enhanced factor could be as high as 10 14 . There are many studies focusing on novel biomarkers for kidney AR using mass spectrometry 9 , Elisa 10 , PCR assay 11 etc.…”

Section: Introductionmentioning

confidence: 99%

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Fiber optic probe enabled by surface-enhanced Raman scattering for early diagnosis of potential acute rejection of kidney transplant

et al. 2014

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We have explored the use of a fiber-optic probe with surface-enhanced Raman scattering (SERS) sensing modality for early, noninvasive and, rapid diagnosis of potential renal acute rejection (AR) and other renal graft dysfunction of kidney transplant patients. Multimode silica optical fiber immobilized with colloidal Ag nanoparticles at the distal end was used for SERS measurements of as-collected urine samples at 632.8 nm excitation wavelength. All patients with abnormal renal graft function (3 AR episodes and 2 graft failure episodes) who were clinically diagnosed independently show common unique SERS spectral features in the urines collected just one day after transplant. SERS-based fiber-optic probe has excellent potential to be a bedside tool for early diagnosis of kidney transplant patients for timely medical intervention of patients at high risk of transplant dysfunction.

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Section: Sers Measurementsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fiber optic probe enabled by surface-enhanced Raman scattering for early diagnosis of potential acute rejection of kidney transplant

et al. 2014

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Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Zhang

Zhou

et al. 2021

Laser & Photonics Reviews

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Optofluidic, as an emerging technology that combines photons and microfluidics, has become a powerful, intelligent, and universal sensing platform in the field of bio-chemical sensing. Optical fiber optofluidic (OFOF), as a branch of optofluidic technology, has stimulated a host of remarkable achievements in the field of bio-chemical sensing due to its superiority of compact structure, immunity to electromagnetic interference, low sample consumption, high sensitivity, and real-time dynamic response. In this paper, an overview of OFOF bio-chemical sensors is presented. The OFOF system architectures are introduced and some advanced functional materials and coating technologies that can be utilized in the OFOF sensing platform to achieve high-performance biochemical sensing are summarized. Research progress and current status of OFOF bio-chemical sensors based on various sensing mechanisms are summarized and analyzed, with emphases on their sensing principles, sensing structures, sensing applications, advantages, and disadvantages. Lastly, the existing challenges and future development trends of OFOF biochemical sensors are briefly discussed.

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PCF with immobilized silver nanoparticles as an optofluidic SERS sensing platform

Cited by 2 publications

References 0 publications

Fiber optic probe enabled by surface-enhanced Raman scattering for early diagnosis of potential acute rejection of kidney transplant

Fiber optic probe enabled by surface-enhanced Raman scattering for early diagnosis of potential acute rejection of kidney transplant

Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

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