pCONus Device for the Endovascular Treatment of Wide-Neck Middle Cerebral Artery Aneurysms

Gory, Benjamin; Aguilar-Pérez, Marta; Pomero, Elisa; Turjman, Francis; Weber, W.; Fischer, Sebastian; Henkes, Hans; Biondi, Alessandra

doi:10.3174/ajnr.a4392

Cited by 46 publications

(31 citation statements)

References 29 publications

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“…Four of the aneurysms in our series were included in a multicenter analysis of 40 middle cerebral artery aneurysms treated with the pCONus device 24. The initial angiographic results were in line with our results and those of Aguilar Pérez et al , with a complete occlusion rate of 25% and a neck remnant in 47.5%.…”

Section: Discussionsupporting

confidence: 88%

Single-center experience in the endovascular treatment of wide-necked intracranial aneurysms with a bridging intra-/extra-aneurysm implant (pCONus)

Fischer

Weber

Titschert

et al. 2015

J NeuroIntervent Surg

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PurposeTo retrospectively evaluate the safety and efficacy of the endovascular treatment of wide-necked intracranial aneurysms assisted by a novel intra-/extra-aneurysm stent-like implant (pCONus).MethodsInitial and follow-up angiographic and clinical results are presented of 25 patients with 25 unruptured and ruptured wide-necked intracranial aneurysms treated by reconstruction of the aneurysm neck using the pCONus implant followed by coil occlusion of the fundus.ResultsSuccessful intra-/extra-aneurysm deployment of the pCONus with coil occlusion of the fundus was achieved in all but one case. Procedure-related ischemic complications were observed in three cases with permanent deterioration in one. Acceptable aneurysm occlusion was achieved in all cases. Follow-up angiography revealed sufficient occlusion in 81.0% of the aneurysms. Intimal hyperplasia in the stented segment of the parent artery or device migration has not been observed to date.ConclusionsThe pCONus device offers a promising treatment option for complex wide-necked bifurcation intracranial aneurysms. Acute or delayed dislocations of coils into the parent artery are successfully avoided.

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Section: Discussionsupporting

confidence: 88%

Single-center experience in the endovascular treatment of wide-necked intracranial aneurysms with a bridging intra-/extra-aneurysm implant (pCONus)

Fischer

Weber

Titschert

et al. 2015

J NeuroIntervent Surg

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“…Immediate angiogram results showed complete occlusion in one patient and 5 small aneurysm and neck remnants. In line with other studies, the overall performance of the device has so far produced satisfactory clinical results [23][24][25][26][27]. There were no significant clinical complications associated with the use of the device and all patients were discharged with no permanent neurological deficits.…”

Section: Discussionsupporting

confidence: 63%

“…There are several studies that have assessed the effectiveness of the pCONus device in unruptured aneurysms but only one currently published study on its use in ruptured aneurysms [23][24][25][26]. Aguilar-Perez et al, 2016, has shown encouraging results in 21 patients with ruptured aneurysms that were treated with the pCONus device [23].…”

Section: Discussionmentioning

confidence: 99%

Endovascular Treatment with the pCONus Device: Initial Experience in a Single UK Centre

Saeed¹

2017

AVS

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“…There are several existing neck bridging devices, including the pCONus1, PulseRider ® , and the eCLIPs™. Numerous case series have been published detailing the use of the pCONus1 in both ruptured and unruptured aneurysms as well as in conjunction with other devices [12][13][14][15][16]. Gory et al [17] recently published their 1-year results on the use of the pCONus1 in wide-necked middle cerebral artery aneurysms.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Wide-Necked Bifurcation Aneurysms

et al. 2018

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Background Recently, numerous devices dedicated to the treatment of wide-necked aneurysms have become available. We present our initial experience with the pCANvas device and present the technical success rate, clinical outcome and immediate angiographic occlusion rates. Objective We sought to determine the efficacy of flow with the pCANvas for the treatment of unruptured intracranial aneurysms. Methods We performed a retrospective review of our prospectively collected data to identify patients treated with the pCANvas device between February 2015 and February 2017. The patient demographics, aneurysm characteristics, immediate and delayed clinical and radiographic follow-up data were recorded. Results We identified 17 patients (13 female) treated only with the pCANvas device. The average age of the patients was 60.5 ± 13.3 years (range 25-75 years). The average dome width was 7.6 ± 3.2 mm (range 3-15.8 mm), dome height 7.1 ± 3.2 mm (range 3-12.9 mm) and neck width 5.4 ± 3.2 (range 3-16.3 mm). The average aspect ratio was 1.5 ± 0.8 (range 0.6-3.7). At the end of the procedure 15 aneurysms continued complete filling of the aneurysm (Raymond Roy Classification[RRC] 3) with 2 aneurysms showing only filling of the neck of the aneurysm (RRC 2). Early follow-up angiography was available for 16 patients and at this stage 11 aneurysms showed persistent and complete filling of the aneurysm (RRC 3), 5 aneurysms showed complete occlusion of the aneurysm (RRC 1) and 7 aneurysms underwent repeat treatment with coiling. Conclusion The early results on the use of the pCANvas are promising; however, longer term follow-up and larger studies are required.

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pCONus Device for the Endovascular Treatment of Wide-Neck Middle Cerebral Artery Aneurysms

Cited by 46 publications

References 29 publications

Single-center experience in the endovascular treatment of wide-necked intracranial aneurysms with a bridging intra-/extra-aneurysm implant (pCONus)

Single-center experience in the endovascular treatment of wide-necked intracranial aneurysms with a bridging intra-/extra-aneurysm implant (pCONus)

Endovascular Treatment with the pCONus Device: Initial Experience in a Single UK Centre

Treatment of Wide-Necked Bifurcation Aneurysms

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