Pcv71 Cost-Utility Analysis in Patients With Drug Refractory Concomitant a Trial Fibrillation in Spain

Gude, MJ López; Bezos, Desiré Rodríguez; Barrios, JM Rodriguez; Contreras, D.

doi:10.1016/s1098-3015(10)66369-3

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“…The lower share of the population with AF that is diagnosed the lower will be the share with anticoagulation treatment. Each patient with AF and thromboembolic risk factors who is not treated with anticoagulation will, in monetary terms, be in on an added financial burden on society [27][28][29], which is double that of the treated patient, because of their higher risk for brain vascular complications. Because a majority of patients with AF with increased risk for stroke had not received anticoagulation therapy, there is a large potential for improvement if the primary care professionals take a more proactive attitude of opportunistic case finding, regardless of the reason of the patient's visit.…”

Section: Discussionmentioning

confidence: 99%

Diagnosed, undiagnosed and overall atrial fibrillation research on population over 60 year-old. AFABE study

Clúa-Espuny¹,

Princep²,

Roso-Llorach³

et al. 2014

Cardio Vasc Syst

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Background: Undiagnosed atrial fibrillation usually is only detected with the first complication. We estimated undiagnosed Atrial Fibrillation prevalence, overall AF and associated factors in a public health-service area in Catalonia, north-eastern Spain. Methods: Multicentre, cross-sectional study, with people randomly selected among the attended population over 60 years old by primary care teams regardless of follow-up time in health centres or at homes. Information was collected through ECGs, electronic medical history reviews and medical interviews. Descriptive and logistic regression analysis was performed. Results: 1043 subjects were recruited (47.1% male), mean age: 73.1 y-o (SD: 7.8 y-o); 43.3% ≥75-year-old. Overall AF prevalence was 10.9% (CI95% 9.1-12.8%); higher in men than in women, progressively increasing with age (24.4% in ≥85-year-old). Only women ≥85-year-old had higher prevalence (26.2%) than men (22.5%). Undiagnosed AF relative prevalence was 2.2% (IC95% 1.3-3.1%). These results show that about 1 in 50 people over 60 years old could suffer undiagnosed AF. The higher risk of AF undiagnosed was found in: men (OR 2.5 IC95% 1.0-6.2), >75 years old (OR 2.5 IC95% 1.0-6.1), heart failure history , who live in rural areas (OR 15.9 IC95% 1.5-160.1) and to whom no one ECG was performed in the last two years. Conclusions: The overall AF prevalence increased 10 times from the sixties to over eighties and the proportion man-woman changes from 4:1 to 1:1. The undiagnosed AF prevalence was 2.2% (IC95% 1.3-3.1). This percentage should be added to the one of untreated cases with OAC.

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Section: Discussionmentioning

confidence: 99%