Pectin / chitosan nanoparticle beads as potential carriers for quercetin release

Nalini, T.; Basha, Sakeenabi; Sadiq, A. Mohamed

doi:10.1016/j.mtcomm.2022.104172

Cited by 23 publications

(10 citation statements)

References 48 publications

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“…When examining the quercetin release studies in the literature, it can be observed that in the study [ 87 ] titled “Pectin/chitosan nanoparticle beads as potential carriers for quercetin release” the percentage encapsulation efficiency (EE) values of the nanoparticles range from 34% to 56.2%, and the loading capacity (LC) values range from 12% to 24.4%. The highest quercetin release was found to be 24% for a duration of 8 h at pH 7.4.…”

Section: Resultsmentioning

confidence: 99%

Quercetin‐loaded sodium alginate/collagen/h‐boron nitride potential wound dressings prepared using the Box‐Behnken experimental design

Çakıcı,

Kaya,

Doğan

et al. 2023

Biotechnology Journal

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Background/aimsNatural and synthetic biocompatible polymers have received significant attention in the pharmaceutical industry due to their rapid and effective healing properties in the wound healing process. The aim of this study was to optimize the extraction of onions, the preparation of sodium alginate/collagen/hydrogen boron nitride (NaAlg/Col/h‐BN) membranes using the Box‐Behnken experimental design, and determine the optimal conditions for quercetin release. The study also aimed to investigate the antimicrobial and antioxidant activities of the prepared membranes and their therapeutic properties.Methods and resultsThe prepared membranes were characterized by Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR), Differential Scanning Calorimetry (DSC), and X‐ray diffraction (XRD). Antimicrobial activities were tested against Gram‐negative (Gr‐) Escherichia coli ATCC 25922, Klebsiella pneumonia, Enterobacter aerogenes, Gram‐positive (Gr+) Staphylococcus aureus ATCC 25923, and Candida albicans ATCC 10231 pathogens. In vitro release studies were conducted to examine the therapeutic properties of the prepared membranes. The optimum conditions for the extraction of onions and the preparation of NaAlg/Col/h‐BN membranes were found to be EtOH = 75 mL, t = 2 h, T = 45°C, and NaAlg = 1.0 g, Col = 2.0 g, and h‐BN = 6% wt, respectively. The prepared membranes exhibited serious antimicrobial properties against S. aureus and C. albicans. The membranes also promoted the controlled release of quercetin for 24 hours in vitro, indicating their potential as a new approach in wound treatment.ConclusionThe study concludes that quercetin‐filled NaAlg/Col/h‐BN membranes have promising therapeutic properties for wound healing. The membranes exhibited significant antimicrobial and antioxidant properties, and their controlled release of quercetin suggests their potential for use in wound healing applications.This article is protected by copyright. All rights reserved

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Section: Resultsmentioning

confidence: 99%

Quercetin‐loaded sodium alginate/collagen/h‐boron nitride potential wound dressings prepared using the Box‐Behnken experimental design

Çakıcı,

Kaya,

Doğan

et al. 2023

Biotechnology Journal

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“…The material showed antifungal activity additionally enhanced by chitosan. The latest reports confirmed the effectiveness of combining pectin with chitosan, where CS/PC nanoparticles were used as quercitin carriers [ 163 ].…”

Section: Complexed Delivery Systemsmentioning

confidence: 96%

Recent Reports on Polysaccharide-Based Materials for Drug Delivery

Kurczewska

2022

Polymers

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Polysaccharides constitute one of the most important families of biopolymers. Natural polysaccharide-based drug delivery systems are of constant interest to the scientific community due to their unique properties: biocompatibility, non-toxicity, biodegradability, and high availability. These promising biomaterials protect sensitive active agents and provide their controlled release in targeted sites. The application of natural polysaccharides as drug delivery systems is also intensively developed by Polish scientists. The present review focuses on case studies from the last few years authored or co-authored by research centers in Poland. A particular emphasis was placed on the diversity of the formulations in terms of the active substance carried, the drug delivery route, the composition of the material, and its preparation method.

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“…The drug release percentage at a given time (t) was calculated using the following formula ( Nalini et al, 2022 ):

…”

Section: Applicationsmentioning

confidence: 99%

Biocompatible gelatin-coated ferrite nanoparticles: A magnetic approach to advanced drug delivery

Shakeel,

Hussain Gul,

John

et al. 2024

Saudi Pharmaceutical Journal

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Pectin / chitosan nanoparticle beads as potential carriers for quercetin release

Cited by 23 publications

References 48 publications

Quercetin‐loaded sodium alginate/collagen/h‐boron nitride potential wound dressings prepared using the Box‐Behnken experimental design

Quercetin‐loaded sodium alginate/collagen/h‐boron nitride potential wound dressings prepared using the Box‐Behnken experimental design

Recent Reports on Polysaccharide-Based Materials for Drug Delivery

Biocompatible gelatin-coated ferrite nanoparticles: A magnetic approach to advanced drug delivery

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