Pediatric Acute Lymphoblastic Leukemia

Abstract

ClassificationEarly classification schema for pALL relied on criteria using the French-American-British (FAB) system, based on morphology and other patient characteristics. The FAB system is no longer AbstractProgress in the understanding and treatment of pediatric acute lymphoblastic leukemia over the past 60 years has been remarkable and it is now expected that 80-85% of children diagnosed will be cured of this disease. This review article discusses risk factors, classification, presentation, risk groups, treatment, outcome, and long-term complications of therapy. Pediatric cancer studies serve as a model for national and international group cooperation to treat uncommon diseases.

Bilateral parotid swelling: An unmissable diagnosis

“…Prognosis and morbidity of acute mumps and ALL are very different. In ALL, early diagnosis and therapy are essential to avoid serious and early complications of this disease 15,16 . Also, treatment for ALL includes a maintenance phase for a total duration of 2–3 years 13 …”

“…In ALL, early diagnosis and therapy are essential to avoid serious and early complications of this disease. 15,16 Also, treatment for ALL includes a maintenance phase for a total duration of 2-3 years. 13 Concerning a parotid swelling with no associated inflammatory signs and with progressive expansion, differential diagnosis should include salivary gland tumour or tumour infiltration of another origin.…”