Pediatric Central Corneal Thickness Variation Among Major Ethnic Populations

Dai, Eric; Gunderson, Charlise A.

doi:10.1016/j.jaapos.2005.12.007

Cited by 56 publications

(21 citation statements)

References 9 publications

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“…Sakalar [15] found CCT reaches adult values around 14 years old. However, others CCT measurements showed no age-related change in healthy children of Czech, Chinese and some other countries [10], [12], [16], [17]. Our results suggested that there is no significant relationship between CCT and age.…”

Section: Discussioncontrasting

confidence: 56%

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Correlation Analysis between Central Corneal Thickness and Intraocular Pressure in Juveniles in Northern China: The Jinan City Eye Study

et al. 2014

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PurposeTo determine the distributions and relation of central corneal thickness (CCT) and intraocular pressure (IOP) by NT-530P in Chinese juveniles, and the effect of gender, age, height, weight and refractive errors on the CTT and IOP.MethodsCCT and IOP of 982 eyes in 514 juveniles aged from 7 to 18 years were measured with NT-530P. Multi-linear regression and ANOVA analysis were used to analyze the relation of CCT and IOP, and the effect of gender, age, height, weight, refractive condition on CCT and IOP respectively.ResultsThe mean CCT and IOP were 554.19±35.46 µm and 15.31±2.57 mmHg. There were significant correlations between the CCT and IOP values. Linear regression analysis revealed a positive correlation between CCT and IOP (r = 0.44, P<0.05). Linear regression equation: IOP = −2.35+0.032CCT, which means the IOP will increase 0.32 mm Hg for every 10-µm increase in CCT. The mean of Corrected IOP (CIOP) was 15.32±2.38 mmHg and had no relation with CCT. There was a negative correlation between refraction degree and CCT (P<0.05), but no correlation between refraction degree and IOP. Multi-linear regression model revealed that the height, weight, age and gender have no effect on the distribution of CCT and IOP respectively.ConclusionsThere is a 0.32 mmHg increase in IOP for every 10-µm increase in CCT. The height, weight, age and gender has no effect on the distribution of CCT and IOP. CCT will become thinner with myopia diopters increases in juveniles. The measurement of CCT is helpful in evaluating the actual IOP correctly.

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Section: Discussioncontrasting

confidence: 56%

“…Some scholars suggested there is no significant relationship between CCT and gender [10], [17], while other reports regarded CCT is thicker in boys than that of girls [12], [15], [18], [19]. Tong [18] reported CCT is thicker about 6.4 µm in boys than girls.…”

Section: Discussionmentioning

confidence: 99%

Correlation Analysis between Central Corneal Thickness and Intraocular Pressure in Juveniles in Northern China: The Jinan City Eye Study

et al. 2014

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“…Osmera et al who examined 124 subjects from 7 to 17 years of age, reported that CCT and intraocular pressure values in Czech children and adults are very similar to those in adults 47. In a study involving 106 children younger than 18 years, Dai et al determined that corneas in children of African American origin were thinner than in Caucasians 48. Further, a survey conducted in Singapore showed that Chinese children had thicker corneas than Malay or Indian children 49…”

Section: Discussionmentioning

confidence: 99%

Age-related changes in central corneal thickness in normal eyes among the adult Lithuanian population

Galgauskas¹,

Juodkaite²,

Tutkuviene³

2014

CIA

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BackgroundThe purpose of this study was to estimate mean central corneal thickness (CCT) and determine whether there are any correlations between CCT, age, and sex in the adult Lithuanian population.MethodsA total of 1,650 Caucasians of Lithuanian origin (aged 18–89 years) comprising 688 (41.7%) men and 962 (58.3%) women were examined. Subjects were stratified by age into seven groups. CCT was measured using ultrasonic pachymetry. Correlations between CCT, age, and sex were sought.ResultsMean (± standard deviation) CCT for both eyes was 544.6±30.5 μm. Mean CCT was 545.2±30.5 μm in the left eye and 544.6±30.5 μm in the right eye, and was 545.0±25.6 μm in men and 544.4±33.5 μm in women. Mean CCT was 550.8±35.7 μm in subjects aged 18–29 years, 557.5±27.6 μm in those aged 30–39 years, 551.3±31.4 μm in those aged 50–59 years, 544.0±31.4 μm in those aged 50–59 years, 544.2±31.6 μm in those aged 60–79 years, 535.1±27.8 μm in those aged 70–79 years, and 530.1±16.8 μm in those aged 80–89 years. No statistically significant difference in CCT was found between the sexes (P>0.05). However, there was a significant difference in subjects aged 18–29 years; men had higher CCT than women (P<0.05). A statistically significant negative correlation was found between CCT and age (r=-0.263, P<0.05) that was stronger in men (r=-0.406, P<0.05) than in women (r=-0.118, P<0.05).ConclusionThe mean CCT in adult Lithuanians was 544.6±30.5 μm, of the left eye 545.2±30.5 μm and of the right – 544.6±30.5 μm. CCT of the right eye was equal to the CCT of both eyes. Mean CCT was 545.0±25.6 μm in men and 544.4±33.5 μm in women. Young men tended to have higher CCT than women. CCT decreases over the lifetime, meaning that older people have thinner corneas. CCT’s dependence on age is stronger in men.

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“…6 Dai reported similar CCT values in Hispanic and white children, but thinner CCT in African-American children. 7 This report was also limited in that most subjects were older than 5 years of age.…”

Section: Introductionmentioning

confidence: 87%

Central Corneal Thickness in Children

Group*¹

2011

Arch Ophthalmol

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Pediatric Central Corneal Thickness Variation Among Major Ethnic Populations

Cited by 56 publications

References 9 publications

Correlation Analysis between Central Corneal Thickness and Intraocular Pressure in Juveniles in Northern China: The Jinan City Eye Study

Correlation Analysis between Central Corneal Thickness and Intraocular Pressure in Juveniles in Northern China: The Jinan City Eye Study

Age-related changes in central corneal thickness in normal eyes among the adult Lithuanian population

Central Corneal Thickness in Children

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