Pediatric pustular psoriasis with Turner's syndrome

Kato, Yoshihiro; Kanazawa, Nobuo; Yamamoto, Toshiyuki

doi:10.1111/1346-8138.13102

Cited by 3 publications

(5 citation statements)

References 5 publications

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“…In addition to increased risk of atopic dermatitis and eczema, we report an increased risk of psoriasis. Multiple case reports have linked Turner syndrome with different psoriatic manifestations [37][38][39][40][41][42], although two epidemiological studies were not able to document a correlation [2,14]. We speculate that this might be due to small study populations, since we, in this larger cohort, report a significantly elevated risk of psoriasis.…”

Section: Discussionmentioning

confidence: 61%

“…We also speculate, that since sensorineural hearing loss advances with age, and since a TS women can act as both HRT non-treated (early life) and later HRT treated, the increased risk might reflect an increased age. Median age in the HRT non-treated group was 30 years old (range 28-31 years) compared with 41 years old (range [40][41][42] in the HRT treated group of TS women. However, further scrutiny of the effect of oestrogens on the inner ear is warranted.…”

Section: Discussionmentioning

confidence: 91%

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Disorders of the eye, ear, skin, and nervous system in women with Turner syndrome –a nationwide cohort study

et al. 2021

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The literature about eye, ear, nose, skin, and nervous system disorders in women with Turner syndrome is equivocal. Impaired vision and hearing in women with Turner syndrome have been described, and case reports of Turner syndrome girls suffering from epilepsy have been published, but no large population-based-studies have explored the occurrence of any of these disorders. We aimed to investigate the risk of admission with disorders related to the eye, ear, nose, skin, and nervous system, compared with background females, and the impact of hormone replacement therapy on these conditions. 1,156 females with TS diagnosed during 1960-2014 were identified using the Danish Cytogenetic Central Registry and linked with personal-level data from the National Patient Registry and the Medication Statistics Registry. Statistics Denmark randomly identified 115,577 age-matched background females. Negative binomial regression was used to analyze hospital discharge diagnoses, reporting incidence rate ratios (IRR). Women with Turner syndrome have an increased risk of developing eye disorders (IRR 4.3 (95% CI 3.5-5.4), including cataract, glaucoma, ocular movement, and accommodation. The risk of ear disorders )) and nose )) was increased in women with Turner syndrome, due to otitis media, cholesteatoma, and hearing loss. Disorders of the nervous system such as epilepsy were increased IRR 6.2 (2.4-15.9), along with skin conditions IRR 2.2 (95%CI 1.7-2.7) like psoriasis, atopic dermatitis, and ingrown nails.

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Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 91%

Disorders of the eye, ear, skin, and nervous system in women with Turner syndrome –a nationwide cohort study

et al. 2021

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“…We previously reported the first case of pediatric with Turner syndrome and pustular psoriasis without hormone therapy. 58 By contrast, pediatric cases of PPP are extremely rare and exceptional. Especially, early onset is almost none, even if adolescent onset may exist.…”

Section: Mutations Of Il-36 Receptor Antagonist (Il-36rn) Have Been Reportedmentioning

confidence: 99%

“…Another patient with Turner syndrome developed vitiligo that coexisted with pustular psoriasis lesions, 57 suggesting a shared aberrant immune condition. We previously reported the first case of pediatric with Turner syndrome and pustular psoriasis without hormone therapy 58 …”

Section: Genetics Of Ppp Versus Gppmentioning

confidence: 99%

Similarity and difference between palmoplantar pustulosis and pustular psoriasis

Yamamoto

2021

The Journal of Dermatology

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Palmoplantar pustulosis (PPP) is characterized by aseptic pustules exclusively occurring on the palms and soles. Pustules arise from vesicles, turning into pustule-vesicles, then pustules, and finally brownish crusts. In 1935, Andrews and Machacek 1 described 15 patients diagnosed as having pustular bacterids of the hands and feet, presenting with chronic recalcitrant sterile pustular eruptions on the palms and soles. Of note, removal of the focal infection resulted in dramatic improvement, suggesting a direct relationship with focal infection. These features are similar to those of Japanese PPP cases.Pustular psoriasis is a rare type of psoriasis, and is roughly classified into generalized or localized forms. Some regard PPP as a localized form or acral variant of pustular psoriasis, while others consider

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“…All these cases were mild and responsive to treatment, as in our case. Mutation analysis was performed in one case, and was also negative . Whether the absence of mutations in IL36RN , AP1S3 and CARD14 is common in patients with TS and GPP warrants further study.…”

mentioning

confidence: 95%

A case of pustular psoriasis possibly precipitated by periodic oestrogen/gestagen therapy for Turner syndrome

et al. 2019

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Pediatric pustular psoriasis with Turner's syndrome

Cited by 3 publications

References 5 publications

Disorders of the eye, ear, skin, and nervous system in women with Turner syndrome –a nationwide cohort study

Disorders of the eye, ear, skin, and nervous system in women with Turner syndrome –a nationwide cohort study

Similarity and difference between palmoplantar pustulosis and pustular psoriasis

A case of pustular psoriasis possibly precipitated by periodic oestrogen/gestagen therapy for Turner syndrome

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