Pediatric Status Asthmaticus

Carroll, Christopher L.; Sala, Kathleen

doi:10.1016/j.ccc.2012.12.001

Cited by 39 publications

(19 citation statements)

References 58 publications

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“…Patients who adhered to their treatment and used their inhalers were protected from status asthmaticus. Our findings agree with previous studies done in pediatric status asthmaticus patients by Chiang et al 18 and Carroll et al 11 They found that poor disease control and an URIT were factors associated with hospital admission.…”

Section: Discussionsupporting

confidence: 77%

Characteristics and outcomes of treatment in status asthmaticus patients at emergency department

Amnuaypattanapon

Limjindaporn

Srivilaithon

et al. 2018

Asian Pac J Allergy Immunol

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Section: Discussionsupporting

confidence: 77%

Characteristics and outcomes of treatment in status asthmaticus patients at emergency department

Amnuaypattanapon

Limjindaporn

Srivilaithon

et al. 2018

Asian Pac J Allergy Immunol

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“…Early and appropriate therapy of ASA result in improved outcome. [ 4 5 6 7 ] Over the last decade, there have been changes in treating acute asthma in view of recently published studies, moving more toward evidence-based medical practices. [ 6 8 9 10 11 12 ]…”

mentioning

confidence: 99%

Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study

Al‐Eyadhy¹,

Temsah²,

Alhaboob³

et al. 2015

Ann Thorac Med

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OBJECTIVES:To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003.METHODS:This is a retrospective observational study. All consecutive pediatric ASA patients who were admitted to PICU during the study period were included. The data were extracted from PICU database and medical records. The Cohort in this study (2013 Cohort) was compared with the Cohort of ASA, which was published in 2003 from the same institution (2003 Cohort).RESULTS:In comparison to previous 2003 Cohort, current Cohort (2013) revealed higher mean age (5.5 vs. 3.6 years; P ≤ 0.001), higher rate of PICU admission (20.3% vs. 3.6%; P ≤ 0.007), less patients who received maintenance inhaled steroids (43.3% vs. 62.4%; P ≤ 0.03), less patients with pH <7.3 (17.9% vs. 42.9%; P ≤ 0.001). There were more patients in 2013 Cohort who received: Inhaled Ipratropium bromide (97% vs. 68%; P ≤ 0.001), intravenous magnesium sulfate (68.2% vs. none), intravenous salbutamol (13.6% vs. 3.6%; P ≤ 0.015), and noninvasive ventilation (NIV) (35.8% vs. none) while no patients were treated with theophylline (none vs. 62.5%). The median length of stay (LOS) was 2 days while mean LOS was half a day longer in the 2013 Cohort. None of our patients required intubation, and there was no mortality.CONCLUSION:We observed slight shift toward older age, considerably increased the rate of PICU admission, increased utilization of Ipratropium bromide, magnesium sulfate, and NIV as important modalities of treatment.

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“…* C ompared with the millions of acute asthma exacerbations occurring in children each year, severe, potentially life-threatening exacerbations are relatively rare, accounting for only about 10,000 annual admissions to an ICU in the United States (1,2). But in a PICU, where all of the illnesses are relatively rare, severe asthma exacerbations are the most common admission diagnoses (1,2). There are few evidence-based treatment strategies, and as a result, after first-line therapies of albuterol and corticosteroids, treatment for severe asthma is highly variable (1)(2)(3).…”

mentioning

confidence: 99%

“…But in a PICU, where all of the illnesses are relatively rare, severe asthma exacerbations are the most common admission diagnoses (1,2). There are few evidence-based treatment strategies, and as a result, after first-line therapies of albuterol and corticosteroids, treatment for severe asthma is highly variable (1)(2)(3). In refractory exacerbations, providers will sometimes use the "kitchen sink" approach, in which multiple different treatments are given all at once in an effort to prevent further deterioration of a critically ill child.…”

mentioning

confidence: 99%