PEG Mediated Eco-Friendly One Pot Sunthesis of Benzylamine Coumarin Derivatives Using Multicomponent Reactant

Viradiya, Denish J.; Kotadiya, V. C.; Khunt, M. D.; Baria, Bharat H.; Bhoya, U. C.

doi:10.18052/www.scipress.com/ilcpa.30.177

Cited by 2 publications

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References 13 publications

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“…One of the methods of overcoming these drawbacks is using the metal oxide nanoparticles as catalysts due to their higher surface-to-volume ratio of nanoparticles (NPs) which is predominantly responsible for their catalytic properties. In addition, they actas paramount adsorbents for the multitude of organic compounds, amplifying the reactivity of the reacting molecules [22,23].…”

Section: Introductionmentioning

confidence: 99%

Novel synthesis of 3-(Phenyl) (ethylamino) methyl)-4-hydroxy-2H-chromen-2-one derivatives using biogenic ZnO nanoparticles and their applications

et al. 2022

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The present work describes the novel synthesis of 3, 3'-((phenyl) (ethylamino) methyl)-4-hydroxy-2H-chromen-2-one derivatives catalyzed by biogenic ZnO nanoparticles. The synthesized heterocyclic compounds were characterized by fourier-transform infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR) andmass spectrometric techniques. Absorption, distribution, metabolism and excretion properties and various toxicities (ADMET) studies and in silico molecular docking studies were carried out for the synthesized compounds. The synthesized compounds were screened for their efficacy towards the antioxidant activity and were subjected to corrosion inhibition study towards the mild steel in acidic medium by weight loss method. Additionally, the recyclability of the employed catalyst was studied.

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Section: Introductionmentioning

confidence: 99%

Novel synthesis of 3-(Phenyl) (ethylamino) methyl)-4-hydroxy-2H-chromen-2-one derivatives using biogenic ZnO nanoparticles and their applications

et al. 2022

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Green Chemistry Approaches to the Synthesis of Coumarin Derivatives

Molnar

Lončarić

Kovač³

2020

COC

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This review is a compilation of the green synthetic methods used in the synthesis of coumarin derivatives. Coumarins are a class of compounds with a pronounced wide range of biological activities, which have found their application in medicine, pharmacology, cosmetics and food industry. Their biological activity and potential application are highly dependent on their structure. Therefore, many researchers have been performing the synthesis of coumarin derivatives on a daily basis. High demands for their synthesis often result in an increased generation of different waste chemicals. In order to minimize the utilization and generation of toxic organic substances, green synthetic methods are applied in this manner. These methods are getting more attention in the last few decades. Green chemistry methods cover a wide range of methods, including the application of ultrasound and microwaves, ionic liquids and deep eutectic solvents, solvent-free synthesis, mechanosynthesis and multicomponent reactions. All typical condensation reactions for coumarin synthesis like Knoevenagel, Perkin, Kostanecki-Robinson, Pechmann and Reformansky reactions, have been successfully performed using these green synthetic methods. According to the authors mentioned in this review, not only these methods reduce the utilization and generation of toxic chemicals, but they can also enhance the reaction performance in terms of product yields, purity, energy consumption and post-synthetic procedures when compared to the conventional methods. Due to the significance of coumarins as biologically active systems and the recent demands of reducing toxic solvents, catalysts and energy consumption, this review provides a first full literature overview on the application of green synthetic methods in the coumarin synthesis. It covers a literature search over the period from 1995-2019. The importance of this work is its comprehensive literature survey on a specific class of heterocyclic compounds, and those researchers working on the coumarin synthesis can find very useful information on the green synthetic approaches to their synthesis. There are some reviews on the coumarin synthesis, but most of them cover only specific reactions on coumarin synthesis and none of them the whole range of green chemistry methods.

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PEG Mediated Eco-Friendly One Pot Sunthesis of Benzylamine Coumarin Derivatives Using Multicomponent Reactant

Cited by 2 publications

References 13 publications

Novel synthesis of 3-(Phenyl) (ethylamino) methyl)-4-hydroxy-2H-chromen-2-one derivatives using biogenic ZnO nanoparticles and their applications

Novel synthesis of 3-(Phenyl) (ethylamino) methyl)-4-hydroxy-2H-chromen-2-one derivatives using biogenic ZnO nanoparticles and their applications

Green Chemistry Approaches to the Synthesis of Coumarin Derivatives

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