Peli1b governs the brain patterning via ERK signaling pathways in zebrafish embryos

Kumar, Ajeet; Anuppalle, Mrudhula; Maddirevula, Sateesh; Huh, Tae‐Lin; Choe, Joonho; Rhee, Myungchull

doi:10.1016/j.gene.2018.12.078

Cited by 7 publications

(4 citation statements)

References 33 publications

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“…As a highly conserved protein and positive regulator in immunity discovered in Drosophila (52), the structure of Pellino in other species is also conserved, e.g., viral Pellino (136), Freshwater Prawn (137), Zebrafish (138), Crassostrea hongkongensis (139), and Japonicas (140). Viral Pellino should be studied further for a poxviral homolog of the Pellino protein capable of inhibiting Tolllike receptor signaling independent of IRAK1 and inhibiting Pellino3-mediated activation of the p38 MAPK pathway (136).…”

Section: Discussionmentioning

confidence: 99%

The Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling

Zhang

2022

Front. Immunol.

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The Pellino family is a novel and well-conserved E3 ubiquitin ligase family and consists of Pellino1, Pellino2, and Pellino3. Each family member exhibits a highly conserved structure providing ubiquitin ligase activity without abrogating cell and structure-specific function. In this review, we mainly summarized the crucial roles of the Pellino family in pattern recognition receptor-related signaling pathways: IL-1R signaling, Toll-like signaling, NOD-like signaling, T-cell and B-cell signaling, and cell death-related TNFR signaling. We also summarized the current information of the Pellino family in tumorigenesis, microRNAs, and other phenotypes. Finally, we discussed the outstanding questions of the Pellino family in immunity.

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Section: Discussionmentioning

confidence: 99%

The Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling

Zhang

2022

Front. Immunol.

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“…In this case, the technique increased the network's lifetime and reduced the loss rate of packets. [43] developed a strategy to control the mobile sink in wireless networks by leveraging the hybrid model to enable path optimization. The mobile-sink node was used to create a moving pattern, and rendezvous points (RPs) were used to travel through every WSN node.…”

Section: ) Random Walk-based Routing Strategymentioning

confidence: 99%

An Overview of Using Mobile Sink Strategies to Provide Sustainable Energy in Wireless Sensor Networks

Majid Lateef,

Kadhum M. Al-Qurabat

2024

IJCDS

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Wireless sensor networks (WSNs) can effectively address the issue with the static sink's sink-hole or hot spot brought on by multi-hop routing by data collecting using mobile sinks (MS). The optimal path's design, however, is a famous NP-hard issue. Data transmission from source nodes to the base station that is both successful and efficient while reducing energy consumption and data loss is what determines the architecture's overall performance. In WSNs, data collection is done via mobile sinks or static sinks (SS). he MS data collection methods are more effective than sink-based approaches because they can gather sensor node data efficiently. Nevertheless, the MS-based data collection methods have a number of shortcomings and restrictions such as energy usage, complexity, cost implications, and scalability issues. Designing a trajectory is therefore an NP-hard task. In this work, we suggest a survey that utilizes path optimization techniques such as swarm intelligence, ant colony optimization (ACO), machine learning and artificial intelligence. We also have an overview of different approaches for using SS and MS-based techniques to collect data from a sensor network, as well as different kinds of data collection using MS and some of the difficulties it encounters. Lastly, we offer a level-based categorization of the various trajectory techniques that were employed to gather the data. We divided schemes into three categories at the first level: static, dynamic, and Hybrid.

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“…Histone ubiquitination has been implicated in various cellular processes and cancers (Cao and Yan, 2012), was shown to be crucial to spermatogenesis (Sheng et al, 2014), and is also an aging biomarker in mammals. In fish, this mark is largely undescribed (Best et al, 2018), but recent zebrafish studies have demonstrated the importance of ubiquitination in brain patterning (Kumar et al, 2019), and of deubiquination in craniofacial development (Ka and Tse, 2017). The general model of the ubiquitination process requires three enzymes: the ubiquitin activation enzyme E1, the ubiquitin conjugating enzyme (E2), and the ubiquitin ligase enzymes (E3), these last enzymes being very diverse (Sheng et al, 2014;Zheng and Shabek, 2017).…”

Section: Histone Ubiquitinationmentioning

confidence: 99%

Genome Survey of Chromatin-Modifying Enzymes in Threespine Stickleback: A Crucial Epigenetic Toolkit for Adaptation?

Fellous

Shama

2019

Front. Mar. Sci.

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Ocean environments are changing rapidly and marine organisms need to cope with these changes in order to survive, develop, and reproduce. To do so, organisms can either migrate, adapt in situ or acclimate via phenotypic plasticity. In this context, the emerging field of environmental epigenetics investigates the contribution of genetic and epigenetic information to adaptive potential of wild populations. Epigenetic modifications are based on the highly dynamic combination of DNA methylation, histone modifications, and non-coding RNAs, which may facilitate phenotypic plasticity through genotype-epigenotype-environment interactions, and can drive rapid evolution in wild populations. However, while knowledge of epigenetic contributions to phenotypes across different developmental and generational timescales is increasing for medical research model species, the mechanistic and synergistic action of these modifications remain comparatively understudied in ecological models such as teleost fishes. Here, we characterized the evolution of the gene toolkit involved in key molecular epigenetic pathways including DNA methylation, histone modifications, macroH2A histone, and miRNA biogenesis/turnover in threespine stickleback, a model species in evolution and ecology. We then investigated these genes within a phylogenetic context by comparing them in stickleback to human, mouse, chicken, tropical clawed frog, zebrafish, medaka, green spotted puffer, channel catfish, and mangrove rivulus. We found that, in general, conserved domains, in conjunction with their phylogenetic positions, suggest evolutionary conservation of putative enzyme activity in stickleback. However, molecular epigenetic pathways also revealed that teleost gene evolution is diversified and complex. Specifically, the number of genes, gene loss/duplication events, identified conserved domains, and putative protein lengths vary greatly from one species to another, particularly within fishes, which exhibit a potentially new class of histone deacetylases. This suggests different biological functions specific to fish species, and that the action of genes regulating epigenetic modifications in model species are not necessarily applicable to other related species. We integrate our results into recent advances concerning epigenetic mechanisms in teleosts, and conclude by discussing the necessity to delve deeper into the fundamental mechanics of epigenetic modifications in a wide array of taxa, particularly those relevant for assisted evolution, conservation, aquaculture, fisheries, and climate change-adaptation studies.

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Peli1b governs the brain patterning via ERK signaling pathways in zebrafish embryos

Cited by 7 publications

References 33 publications

The Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling

The Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling

An Overview of Using Mobile Sink Strategies to Provide Sustainable Energy in Wireless Sensor Networks

Genome Survey of Chromatin-Modifying Enzymes in Threespine Stickleback: A Crucial Epigenetic Toolkit for Adaptation?

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