Pemphigoid Gestationis

Kukkamalla, Rene; Bayless, Patricia

doi:10.5811/cpcem.2018.11.39258

Cited by 5 publications

(5 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Clinically PG manifests with severe pruritus and polymorphic inflammatory skin lesions: eczematous or erythema multiforme-like lesions, urticaria-like lesions, papules that can evolve into tense blisters/bullae. The rash usually start in the periumbilical area and can spread to the whole abdomen and limbs; the mucosae are spared [ 55 , 56 ].…”

Section: Autoimmune Disordersmentioning

confidence: 99%

Urticaria: A Narrative Overview of Differential Diagnosis

et al. 2023

View full text Add to dashboard Cite

Urticaria is an inflammatory skin disorder that may occur in isolation or associated with angioedema and/or anaphylaxis. Clinically, it is characterized by the presence of smooth, erythematous or blanching, itchy swelling, called wheals or hives, which greatly vary in size and shape and last less than 24 h before fading to leave normal skin. Urticaria is the consequence of mast-cell degranulation that can be caused by immunological or non-immunological mechanisms. From a clinical point of view, many skin conditions can mimic urticaria and their recognition is mandatory for a correct management and therapeutic approach. We have reviewed all of the main relevant studies which addressed differential diagnosis of urticarial, published until December 2022. The National Library of Medicine PubMed database was used for the electronic research. The present review offers a clinical narrative overview, based on the available literature, of the principal skin disorders that can be misdiagnosed as urticaria (mainly autoinflammatory or autoimmune disorders, drug-induced reactions, and hyperproliferative diseases). The aim of this review is to provide clinicians a useful tool for correctly suspecting and identifying all of these conditions.

show abstract

Section: Autoimmune Disordersmentioning

confidence: 99%

Urticaria: A Narrative Overview of Differential Diagnosis

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Esta dermatosis se distribuye de manera mundial y sin diferencia entre las etnias (3,4). Se caracteriza por ser exclusiva del periodo gestacional y postparto inmediato, donde se presenta con mayor incidencia entre el segundo y tercer trimestre (3,(5)(6)(7), sin embargo puede presentarse desde el primer trimestre (8).…”

Section: Epidemiologíaunclassified

“…El penfigoide gestacional (PG) es una dermatosis bulosa, subepidermal, autoinmune y rara que asocia riesgos materno-fetales (1,2); identificada por primera vez en 1872 por John Laws Milton. Clínicamente se va a presentar, principalmente entre el segundo y tercer trimestre (3)(4)(5)(6)(7), con prurito intenso, acompañado de pápulas urticarianas, las cuales, posteriormente confluyen a placas y son seguidas por una erupción ampollosa (3,(8)(9)(10), esta inicia a nivel periumbilical con posterior diseminación al resto del cuerpo (2,3,11), respetando el área de la cara y las mucosas (9). Para el diagnóstico, este se basa en la clínica, biopsia, la inmunofluorescencia directa y ELISA (10,12).…”

Section: Introductionunclassified

See 1 more Smart Citation

Penfigoide gestacional, una dermatosis que se debe conocer

2020

View full text Add to dashboard Cite

El penfigoide gestacional (PG) es una enfermedad cutánea rara, prurítica, autoinmune, y pertenece a las dermatosis del embarazo. Esta ocurre principalmente entre el segundo, tercer trimestre y/o posparto inmediato, con un brote vesiculobuloso pruriginoso de inicio periumbilical. El diagnóstico se basa en la clínica, histología de la lesión, inmunofluorescencia directa y ELISA. La mayoría de los casos se trata con antihistamínicos y corticoesteroides. El PG está asociado con aumento de la morbilidad en las embarazadas y riesgos fetales, y por dicha razón, es importante el reconocimiento de la patología para brindar un adecuado manejo interdisciplinario con dermatología, obstetricia y anatomía patológica.

show abstract

“…Pemphigoid gestation (PG) is an autoimmune bullous disease that occurs during pregnancy or the puerperium[ 1 ]. The main clinical manifestations are tension blisters and bullae with urticaria-like plaques, accompanied by pruritus[ 2 ]. For approximately 14%-25% of patients in the postpartum period, menstrual periods and oral contraceptive drugs may induce or aggravate the disease[ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Diagnosis, fetal risk and treatment of pemphigoid gestationis in pregnancy: A case report

Jiao¹,

Ruan²,

Liu³

et al. 2021

WJCC

View full text Add to dashboard Cite

BACKGROUND Pemphigoid gestationis (PG) is a rare autoimmune blistering disease that usually presents in the second or third trimester, with an incidence of 1 per 50000 pregnancies. PG tends to recur with an earlier onset and a more severe course in subsequent pregnancies. Skin biopsy markers can be confirmed by direct immunofluorescence staining. CASE SUMMARY Our patient was diagnosed with PG at 8 mo of gestation with fresh bullous lesion marks on the abdomen and limbs. Termination of the pregnancy was performed by cesarean section at 37 + 4 wk of gestation. The patient delivered an infant weighing 3620 gm. The infant had urticaria-like and vesicular skin lesions and was diagnosed with PG. The patient was discharged on prednisolone and in a satisfactory condition. The infant was discharged after anti-inflammatory therapy for one week. CONCLUSION PG is a rarely reported disease, and 10% of newborns develop mild clinical symptoms consisting of urticaria-like or vesicular skin lesions. We intend to remind clinicians to consider this condition when a patient presents with such lesions so that treatment can be started early and neonatal morbidity can be taken into account.

show abstract

Pemphigoid Gestationis

Cited by 5 publications

References 3 publications

Urticaria: A Narrative Overview of Differential Diagnosis

Urticaria: A Narrative Overview of Differential Diagnosis

Penfigoide gestacional, una dermatosis que se debe conocer

Diagnosis, fetal risk and treatment of pemphigoid gestationis in pregnancy: A case report

Contact Info

Product

Resources

About