Penoscrotal Transposition: A Case Report

A rare case of complete penoscrotal transposition with hypospadias in a newborn

“…PST is a very rare clinical situation in which the scrotum is located anterior and superior to the penis and a severe degree of PST, as in our case, with hypospadias and normal scrotum have been infrequently reported in medical literature ( 1 , 3 , 4 ) . During normal human maturation, scrotal swellings move inferomedially during the 9 th -11 th week, and fuse in the midline caudal to the penis by the 12 th week of gestation ( 4 ) .…”

“…Penoscrotal transposition (PST) is an infrequent congenital external genital malformation in which the scrotum is located superior and anterior to the penis ( 1 ) . PST can be defined as either complete or incomplete according to the positional exchanges between the penis and scrotum and both forms of PST are generally linked with hypospadias.…”

“…The primary cause of this rare clinical disorder is a fusion defect or delay of urethral folds. Embryologically, PST is considered to result from abnormal genital tubercle development around the 6 th -7 th week of gestation ( 1 ) .…”

Prenatal diagnosis of complete penoscrotal transposition with normal scrotum: Two case reports and review of the literature

“…Other differential diagnoses in the postnatal period are micropenis, penoscrotal hypospadias, and penile agenesis with skin tag anterior to the anus. 21 This developmental anomaly can also be seen in female fetuses as clitoris and Labia minor are placed caudally to labia majora. 7…”

An Overview of Hypospadias Surgery

“…The size of the phallus and its potential to develop into a sexually satisfactory penis at puberty should be carefully evaluated before surgery. Reassignment to female gender may even be a prudent therapeutic option in a small number of extreme penoscrotal transposition cases due to the unsatisfactory results obtained with penile repositioning and reconstruction [30].…”