Perceived Improvement and Satisfaction With Training After Individualized-Targeted Computerized Cognitive Training in Adults With HIV-Associated Neurocognitive Disorder Living in Alabama: A Descriptive Cross-sectional Study

Byun, Jun Y; Azuero, Andres; Fazeli, Pariya L; Li, Wei; Lambert, Crystal Chapman; Bene, Victor A. Del; Triebel, Kristen; Jacob, Alexandra; Vance, David E.

doi:10.1097/jnc.0000000000000333

J Assoc Nurses AIDS Care

2022

DOI: 10.1097/jnc.0000000000000333

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Perceived Improvement and Satisfaction With Training After Individualized-Targeted Computerized Cognitive Training in Adults With HIV-Associated Neurocognitive Disorder Living in Alabama: A Descriptive Cross-sectional Study

Jun Y Byun¹,

Andres Azuero²,

Pariya L Fazeli³

et al.

Abstract: Nearly 30-50% of people living with HIV (PLWH) have HIV-associated neurocognitive disorder. m Individualized-targeted computerized cognitive training may improve cognition and everyday functioning in select domains. m PLWH perceived improvement in overall cognitive domains and everyday functioning after individualized-targeted computerized cognitive training.m As older PLWH have concerns about cognitive decline, cognitive training may assuage their concerns and empower them by providing an activity that might … Show more

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2024

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Cited by 2 publications

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A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study

Vance,

Fazeli,

Azuero

et al. 2024

AIDS Behav

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Nearly 40% of people with HIV (PWH) experience HIV-associated Neurocognitive Disorder (HAND). In this 3-group efficacy study, 216 PWH 40 + years with HAND or borderline HAND were randomized to either: (1) 10 h of SOP training (n = 70); (2) 20 h of SOP training (n = 73), or (3) 10 h of Internet navigation training (n = 73; contact control group). Participants were administered a measure of SOP [i.e., the Useful Field of View Test (UFOV®)] at baseline, at posttest immediately after training, and at year 1 and year 2 follow up. Intent-to-treat linear mixed-effect models with subject-specific intercept and slope were fitted to estimate between-group mean differences at the follow-up time-points. At the post-intervention time-point, small beneficial SOP training effects were observed for the 10-h group in UFOV® total (d = 0.28, p = 0.002). Effects were of larger magnitude for the 20-h group in these same outcomes [UFOV® total (d = 0.43, p < 0.001)]. These results indicated better benefit with more training. No intervention effect was observed at year 1. At year 2, beneficial effects of small magnitude were observed again in the 10-h group [UFOV® total (d = 0.22, p = 0.253)] with larger small-to-moderate magnitude in the 20-h group [UFOV® total (d = 0.32, p = 0.104)]. This study suggests that SOP training can improve a key indicator of this cognitive performance and that treatment gains are small-to-moderate over a two-year period. Prior literature suggests slower SOP is predictive of impairment in everyday functioning in older PWH; such an approach could potentially improve everyday functioning in PWH.

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A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study

Vance,

Fazeli,

Azuero

et al. 2024

AIDS Behav

View full text Add to dashboard Cite

show abstract

Cognitive impairment in people living with HIV: mechanisms, controversies, and future perspectives

Moschopoulos,

Alford,

Antoniadou

et al. 2024

Trends in Molecular Medicine

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Perceived Improvement and Satisfaction With Training After Individualized-Targeted Computerized Cognitive Training in Adults With HIV-Associated Neurocognitive Disorder Living in Alabama: A Descriptive Cross-sectional Study

Cited by 2 publications

References 14 publications

A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study

A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study

Cognitive impairment in people living with HIV: mechanisms, controversies, and future perspectives

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