Percutaneous Computed Tomography-guided Fine Needle Brachytherapy of Pulmonary Malignancies

Brach, Bernard B.; Buhler, C; Hayman, Michael H.; Joyner, Lee Roy; Liprie, Samuel F.

doi:10.1378/chest.106.1.268

Cited by 21 publications

(13 citation statements)

References 4 publications

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“…Future developments in imaging based patient management mainly concern oncological applications. Following preliminary studies on percutaneous treatment of inoperable or early non-small cell lung cancer, such as electrochemical polarization of cancer [199], new modalities are emerging including percutaneous brachytherapy [200] and radiofrequency tumour ablation [201]. Interventional radiology will also be used for catheter or needle mediated immunomodulatory or gene therapy delivery to the target organs.…”

Section: Resultsmentioning

confidence: 99%

Imaging guided thoracic interventions

Ghaye¹,

Dondelinger²

2001

Eur Respir J

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Interventional Radiology is a technique based medical specialty, using all available imaging modalities (¯uoroscopy, ultrasound, computed tomography, magnetic resonance, angiography) for guidance of interventional techniques for diagnostic or therapeutic purposes.Actual, percutaneous transthoracic needle biopsy includes core needle biopsy besides ®ne needle aspiration. Any pleural, pulmonary or mediastinal¯uid or gas collection is amenable to percutaneous pulmonary catheter drainage.Treatment of haemoptysis of the bronchial artery or pulmonary artery origin, transcatheter embolization of pulmonary arteriovenous malformations and pseudoaneurysms, angioplasty and stenting of the superior vena caval system and percutaneous foreign body retrieval are well established routine procedures, precluding unnecessary surgery. These techniques are safe and effective in experienced hands.Computed tomography is helpful in pre-and postoperative imaging of patients being considered for endobronchial stenting. Many procedures can be performed on an outpatient basis, thus increasing the cost-effectiveness of radiologically guided interventions in the thorax.

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Section: Resultsmentioning

confidence: 99%

Imaging guided thoracic interventions

Ghaye¹,

Dondelinger²

2001

Eur Respir J

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“…HDR interstitial brachytherapy has been utilized to treat peripherally situated primary or metastatic cancers, although the clinical experience is limited to small groups of patients [13]. Brach and colleagues used computed tomography-guided fine needle percutaneous implantation for direct intralesional HDR brachytherapy for small (<2 cm) pulmonary lesions in 20 patients with primary lung cancer or metastatic cancer which involved the lung or chest wall.…”

Section: Clinical Results: Definitive Treatment Interstitial Brachythmentioning

confidence: 99%

Brachytherapy in lung cancer

Gaspar

1998

J. Surg. Oncol.

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“…In previous studies (27,28), pneumothorax and hemoptysis were the predominant complications of 125 I seed implantation. However, in the present study, the two groups did not significantly differ in the rates of pneumothorax and hemoptysis or focal hemorrhage, and all patients were successfully treated using appropriate therapies.…”

mentioning

confidence: 87%

Sodium glycididazole enhances the efficacy of combined iodine-125 seed implantation and chemotherapy in patients with non small-cell lung cancer

Zhang

Wang

2015

Oncology Letters

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Abstract. The aim of the present study was to investigate the efficacy and safety of combined therapy with iodine-125 seed implantation and the gemcitabine plus cisplatin chemotherapeutic regimen, as well as treatment with the radiosensitizer sodium glycididazole (CMNa), in patients with non-small cell lung cancer (NSCLC). The 40 patients with NSCLC in the experimental group (19 females; mean age, 52.3±11.5 years; age range, 34-74 years) received the combined therapy and CMNa, and the 41 controls (13 females; mean age, 53.7±10.7 years; age range, 8-79 years) received the combined therapy only. The response rate in the experimental group was significantly higher than in the control group (85.5 vs. 63.4%; P=0.027), with no apparent complications. Therefore, it was concluded that such therapy may be reliable and well-tolerated for the treatment of patients with NSCLC.

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Percutaneous Computed Tomography-guided Fine Needle Brachytherapy of Pulmonary Malignancies

Cited by 21 publications

References 4 publications

Imaging guided thoracic interventions

Imaging guided thoracic interventions

Brachytherapy in lung cancer

Sodium glycididazole enhances the efficacy of combined iodine-125 seed implantation and chemotherapy in patients with non small-cell lung cancer

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