Percutaneous Vertebroplasty for Osteoporotic Compression Fractures: Quantitative Prospective Evaluation of Long-term Outcomes

Kyphoplasty and Vertebroplasty Produce the Same Degree of Height Restoration

“…This result is in accordance with a previous study that had shown that cement extravasation can be seen in up to 88% of vertebroplasties [1][2][3][4][5][6][7][8][9][10] but up to 33% of kyphoplasties. 10,[19][20][21][22][23][24][25][26][27][28] With 1 exception, 30 other studies have also shown more frequent cement leakage with vertebroplasty than with kyphoplasty.…”

“…[1][2][3][4][5][6][7][8][9][10] The main goal of vertebroplasty is to relieve pain for patients in whom conservative treatment has failed. Restoration of vertebral body height is a secondary goal, and previous studies have shown that vertebroplasty can achieve some height restoration.…”

Natural History of Pain in Patients with Conservatively Treated Osteoporotic Vertebral Compression Fractures: Results from VERTOS II

“…Most results are based on retrospective observational studies. [7][8][9][10] Recently, 3 randomized controlled trials concerning vertebroplasty have been published with conflicting results. Investigators in 2 trials 11,12 concluded that there is no benefit to vertebroplasty over a sham placebo procedure involving the injection of local anesthetic into the area adjacent to the fracture.…”

Differences in endplate deformation of the adjacent and augmented vertebra following cement augmentation

“…A total of 700,000 vertebral fractures are reported in US each year, outnumbering fractures of the hip and ankle combined [6,43,48,54]. Vertebral fractures may result in local pain about the fracture site, loss of height due to vertebral collapse, spinal instability and in many cases kyphotic deformity [45].…”