Pérdida en el seguimiento de pacientes tratados por tuberculosis resistente a rifampicina o multidrogorresistente en Ecuador

Tatés-Ortega, Nelly; Alvarez, Juan; López, Lucelly; Mendoza-Ticona, Alberto; Alarcón-Arrascue, E

doi:10.26633/rpsp.2019.91

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…Pacientes com histórico de abandono do tratamento possuem determinantes sociais que aumentam as chances dessa escolha vir a se repetir, sendo necessário que os profissionais de saúde realizem um acompanhamento robusto dos pacientes com a doença, adequando o tratamento a realidade dos mesmos, a fim de minimizar o risco de desfechos negativos 34 .…”

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Completude do Sistema de Informação em Tuberculose no estado do Paraná, 2008-2017: estudo ecológico

et al. 2020

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Objetivo: analisar a completude dos dados de tuberculose no Sistema de Informação de Agravos de Notificação (SINAN). Método: estudo ecológico composto por casos notificados de tuberculose tratados no Paraná entre 2008-2017. Os dados foram agrupados em variáveis de notificação, acompanhamento e complementares e compreendiam informações de preenchimento obrigatórias e essenciais. Classificou-se a completude como excelente (<5% de incompletude), boa (5 a <10%), regular (10 a <20%), ruim (20 a 50%) e muito ruim (>50%). A pesquisa atende a resolução 510/2016 do Conselho Nacional de Saúde. Resultados: variáveis obrigatórias apresentaram menos de 5% de incompletude, as essenciais tiveram avaliação muito ruim para teste de sensibilidade, tabagismo, drogas ilícitas. Completude do grupo acompanhamento piorou ao longo dos anos, demais grupos apresentaram melhora, exceto em 2014. Conclusão: completude insatisfatória em parte das variáveis essenciais e diminuição da completude no grupo acompanhamento revela repercussão no vinculo individuo-serviço de saúde e no desfecho dos casos.

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Completude do Sistema de Informação em Tuberculose no estado do Paraná, 2008-2017: estudo ecológico

et al. 2020

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Efficacy of a shorter chemotherapy regimen in a patient with drug-resistant tuberculosis with early surgical intervention

Chumovatov

Komissarova

Chernyh

et al. 2023

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Introduction. Treatment for multidrug-resistant tuberculosis lasts 18 to 24 months, so there is a high rate of therapy interruptions, including patient-initiated interruptions. In recent years, the use of shorter regimens for the treatment of multidrug-resistant tuberculosis has been actively discussed around the world. The first use of shorter chemotherapy regimens was conducted in three regions of the Russian Federation in 2019. However, the prevalence of the use of shorter chemotherapy regimens in our country remains low.The purpose of the study was to demonstrate the high efficacy of a shortened chemotherapy regimen with surgical intervention.Materials and methods. In the conditions of the Central Research Institute of Tuberculosis, the patient underwent a comprehensive examination, including mandatory, additional and optional methods of investigation. Based on the findings of the comprehensive examination and established broad drug resistance of Mycobacterium tuberculosis, a shorter course of chemotherapy was prescribed and surgical treatment was performed after 2 months of therapy.Results and Discussion It was decided to carry out anti-tuberculosis therapy according to a shortened scheme in the amounts: Linezolid, Bedaquiline, Cycloserine, Levofloxacin, Pyrazinamide. Taking into account positive radiological dynamics after two months of treatment and absence of contraindications, early surgery intervention was performed. At the end of a nine-month course of chemotherapy the patient had a stable radiological picture, “fresh” focal and infiltrative changes in the lungs were not detected. Early surgical treatment with a shorter chemotherapy regimen may become a highly effective method in the cure of drug-resistant tuberculosis in the Russian Federation.Conclusion. A shorter chemotherapy regimen with optimal timing of surgical intervention is highly effective and safe to use.

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Pérdida en el seguimiento de pacientes tratados por tuberculosis resistente a rifampicina o multidrogorresistente en Ecuador

Cited by 2 publications

References 21 publications

Completude do Sistema de Informação em Tuberculose no estado do Paraná, 2008-2017: estudo ecológico

Completude do Sistema de Informação em Tuberculose no estado do Paraná, 2008-2017: estudo ecológico

Efficacy of a shorter chemotherapy regimen in a patient with drug-resistant tuberculosis with early surgical intervention

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