Perfil antropométrico e distribuição da gordura corpórea relacionados ao risco cardiovascular em adultos vivendo com HIV/AIDS

Prevalence of HIV-Associated Lipodystrophy in Brazil: A Systematic Review of the Literature

“…On the other hand, no patient with less than one year of pharmacological treatment had lipodystrophy. Studies have reported the association between lipodystrophy incidence and longterm antiretroviral therapy [18,23,[28][29][30].…”

“…In the study by Diehl et al [18], lipodystrophy was observed in 27% of individuals living with HIV who had never used HAART. Some studies have shown that patients with longer HIV infection and exposed to HAART had higher prevalence of lipodystrophy than their counterparts [17,18,23,24,28,29].…”

“…Not all the surveyed patients developed lipodystrophy associated with HIV [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31], which suggests that lipodystrophy syndrome varies not only with respect to the length of time of the treatment regimen, but also in relation to the effects of systemic chronic inflammatory process resulting from HIV infection itself and factors associated with lifestyle such as physical activity, dietary pattern, and other factors [23,36,37]. There are few studies in the literature comparing these changes with those of non-HIV-infected individuals, because a fat gain can happen with natural aging, or as an immune recovery process after initiation of HAART regimen [38,39].…”

“…Table 1 shows the characteristics of the Brazilian studies included in the review with estimates of prevalence of lipodystrophy in people living with HIV. With regard to the study design, 14 were crosssectional studies [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31], and 1 was a retrospective cohort study [19].…”

“…The main objective of most reviewed studies was to identify the prevalence of lipodystrophy in people living with HIV in Brazil [17,18,23,[29][30][31]. The remaining papers were intended to assess metabolic changes, and lipodystrophy was a secondary outcome [19][20][21][22][24][25][26][27][28].…”