Performance Evaluation of a Continuous Glucose Monitoring System under Conditions Similar to Daily Life

Abstract

Abbreviations: (BG)

Evaluation of the Performance of a Novel System for Continuous Glucose Monitoring

“…6,[13][14][15][16] Some of the reported performance data of available CGM systems were obtained with similar procedures under similar conditions, thus allowing for an appropriate comparison to the results presented here. 6,16 The observed improvement in CGM performance over the usage period has already been reported for other CGM systems. 6,10,16,17 However, performance of the prototype sensor was noticeably constant over the study period.…”

“…20,22 In this evaluation, the MARD and the PARD were remarkably better during induced glucose fluctuations compared with available CGM systems. 6,16 This suggests a decreased device-dependent time delay, as the physiological delay is assumed to be constant/comparable among CGM systems.…”

“…However, compared with currently available CGM systems, the sensor's performance in this range was remarkably better. 5,6,[13][14][15][16][17] One factor that potentially affects the performance of CGM systems is the time delay of these systems, particularly during rapid changes in glycemia. 20,21 Such time delays are caused by two factors: (1) a physiological delay between changes in BG and interstitial glucose and (2) device-dependent delays in measurement.…”

Performance Evaluation of Three Continuous Glucose Monitoring Systems: Comparison of Six Sensors Per Subject in Parallel

“…The Seven Plus's successor, the DexCom G4 Platinum (DexCom, San Diego, CA) is reported to be more accurate, 24 and the Navigator was replaced by the FreeStyle Navigator II (Abbott Diabetes Care, Alameda, CA). However, it is unclear if its performance has changed.…”

Assessing Sensor Accuracy for Non-Adjunct Use of Continuous Glucose Monitoring

“…20 Nevertheless, the accuracy of CGM is increasing and may be approaching a physiological limit for subcutaneous glucose monitoring. [21][22][23][24][25][26][27] CGM data and information CGM generates data streams that are both voluminous and complex. From an analytical point of view, these data are time series-sequences of BG readings that are equally spaced in time (e.g., every 5 min).…”