Performance evaluation of a subset of a four-layer LSO detector for a small animal DOI PET scanner: jPET-RD

Tsuda, Tomoaki; Murayama, Hideo; Kitamura, Kazuhiro; Inadama, Naoko; Yamaya, Taiga; Yoshida, Eiji; Nishikido, Fumihiko; Hamamoto, M.; Kawai, H.; Ono, Yusuke

doi:10.1109/tns.2005.862961

Cited by 70 publications

(32 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most DOI detectors employ light sharing over several photosensors, utilize crystals with varied decay time constant, or deliberately alter light collection/wavelength along a scintillator crystal. [21][22][23][24][25][26][27][28][29] This, inevitably, in most cases slows the rise-time and reduces signal-to-noise ratio of the detector signal, compromising timing performance. 15 It is therefore, extremely challenging to fabricate a high performance TOF detector that also provides fine DOI resolution.…”

Section: Background and Theorymentioning

confidence: 99%

Side readout of long scintillation crystal elements with digital SiPM for TOF‐DOI PET

2014

View full text Add to dashboard Cite

Purpose: Side readout of scintillation light from crystal elements in positron emission tomography (PET) is an alternative to conventional end-readout configurations, with the benefit of being able to provide accurate depth-of-interaction (DOI) information and good energy resolution while achieving excellent timing resolution required for time-of-flight PET. This paper explores different readout geometries of scintillation crystal elements with the goal of achieving a detector that simultaneously achieves excellent timing resolution, energy resolution, spatial resolution, and photon sensitivity. Methods: The performance of discrete LYSO scintillation elements of different lengths read out from the end/side with digital silicon photomultipliers (dSiPMs) has been assessed. Results: Compared to 3 × 3 × 20 mm 3 LYSO crystals read out from their ends with a coincidence resolving time (CRT) of 162 ± 6 ps FWHM and saturated energy spectra, a side-readout configuration achieved an excellent CRT of 144 ± 2 ps FWHM after correcting for timing skews within the dSiPM and an energy resolution of 11.8% ± 0.2% without requiring energy saturation correction. Using a maximum likelihood estimation method on individual dSiPM pixel response that corresponds to different 511 keV photon interaction positions, the DOI resolution of this 3 × 3 × 20 mm 3 crystal side-readout configuration was computed to be 0.8 mm FWHM with negligible artifacts at the crystal ends. On the other hand, with smaller 3 × 3 × 5 mm 3 LYSO crystals that can also be tiled/stacked to provide DOI information, a timing resolution of 134 ± 6 ps was attained but produced highly saturated energy spectra. Conclusions: The energy, timing, and DOI resolution information extracted from the side of long scintillation crystal elements coupled to dSiPM have been acquired for the first time. The authors conclude in this proof of concept study that such detector configuration has the potential to enable outstanding detector performance in terms of timing, energy, and DOI resolution. C 2014 American Association of Physicists in Medicine. [http://dx

show abstract

Section: Background and Theorymentioning

confidence: 99%

Side readout of long scintillation crystal elements with digital SiPM for TOF‐DOI PET

2014

View full text Add to dashboard Cite

show abstract

“…Parallax correction is usually based on a measurement of the interaction depth of the photon, either in a discrete way (e.g., phoswich [8] or a pixel-encoding scheme [9]) or in a continuous way (e.g., using the ratio of the signal measured on the top and bottom side of the scintillator [10]). Hence, the accuracy on the estimated true interaction position in the scintillator depends on the accuracy of the estimated position of the photon in the plane of the photo detector and on the accuracy of the DOI measurement.…”

Section: Incidence Versus Interaction Positionmentioning

confidence: 99%

Towards a continuous crystal APD-based PET detector design

Bruyndonckx

Lemaître

Schaart

et al. 2007

Nuclear Instruments and Methods in Physics Research Section A:

View full text Add to dashboard Cite

“…This is because reconstructed images in the open gap are generated only from oblique LORs. A depth-of-interaction (DOI) detector [6][7][8][9][10] can compensate for this problem.…”

Section: Introductionmentioning

confidence: 99%

“…We have developed and evaluated a small OpenPET prototype that uses 4-layer DOI detectors [10], which offers the promise of high sensitivity (6.5% system sensitivity) and high spatial resolution (about 2 mm full width at half maximum (FWHM)) [13]. The system design of the small OpenPET prototype has been optimized for in-beam PET experiments.…”

Section: Introductionmentioning

confidence: 99%

System design of a small OpenPET prototype with 4-layer DOI detectors

Yoshida¹,

Kinouchi

Tashima³

et al. 2011

Radiol Phys Technol

View full text Add to dashboard Cite

We have proposed an OpenPET geometry which consists of two axially separated detector rings. The open gap is suitable for in-beam PET. We have developed the small prototype of the OpenPET especially for a proof of concept of in-beam imaging. This paper presents an overview of the main features implemented in this prototype. We also evaluated the detector performance. This prototype was designed with 2 detector rings having 8 depth-of-interaction detectors. Each detector consisted of 784 Lu(2x)Gd(2(1-x))SiO₅:Ce (LGSO) which were arranged in a 4-layer design, coupled to a position-sensitive photomultiplier tube (PS-PMT). The size of the LGSO array was smaller than the sensitive area of the PS-PMT, so that we could obtain sufficient LGSO identification. Peripheral LGSOs near the open gap directly detect the gamma rays on the side face in the OpenPET geometry. Output signals of two detectors stacked axially were projected onto one 2-dimensional position histogram for reduction of the scale of a coincidence processor. Front-end circuits were separated from the detector head by 1.2-m coaxial cables for the protection of electronic circuits from radiation damage. The detectors had sufficient crystal identification capability. Cross talk between the combined two detectors could be ignored. The timing and energy resolutions were 3.0 ns and 14%, respectively. The coincidence window was set 20 ns, because the timing histogram showed that not only the main peak, but also two small shifted peaks were caused by the coaxial cable. However, the detector offers the promise of sufficient performance, because random coincidences are at a nearly undetectable level for in-beam PET experiments.

show abstract

Performance evaluation of a subset of a four-layer LSO detector for a small animal DOI PET scanner: jPET-RD

Cited by 70 publications

References 5 publications

Side readout of long scintillation crystal elements with digital SiPM for TOF‐DOI PET

Side readout of long scintillation crystal elements with digital SiPM for TOF‐DOI PET

Towards a continuous crystal APD-based PET detector design

System design of a small OpenPET prototype with 4-layer DOI detectors

Contact Info

Product

Resources

About