In wireless communications, it is very tedious task to achieve the best performance without losing any data and time. It is also a challenging work to select an appropriate routing protocol in different network scenarios in respect of several performance parameters. In this research work reactive and proactive routing protocols are evaluated by considering six performance parameters. Especially multipath-based routing protocols have been compared. Network scenarios are generated by varying the pause time, network size, simulation time, speed, number of nodes, network connections, and packet size. Performance parameters are considered as throughput, packet delivery ratio, average end to end delay, total dropped packets, jitter, and total received packets. Experimental work is conducted on network simulator NS-2.35 and results are tabulated for analytical discussion purpose. In most of the cases simulation results clearly indicate that, Ad-hoc on Demand Multi-path Distance Vector (AOMDV) and Destination Sequenced Distance Vector (DSDV) routing protocols shows excellence performance. In some cases, Multi-path Dynamic Address Routing Techniques (M-DART) routing protocol works well as compared to Ad hoc on Demand Distance Vector (AODV) and DSDV.