Peri‐implant soft tissues around implants with a modified neck surface. Part 1. Clinical and histometric outcomes: a pilot study in minipigs

Liñares, Antonio; Domken, Olivier; Dard, Michel; Blanco, Juan

doi:10.1111/jcpe.12068

Cited by 14 publications

(27 citation statements)

References 36 publications

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“…The soft tissue buccal dimensions were similar to the ones reported in a recently published publication in mesio‐distal sections (Liñares et al. ), and those published in similar preclinal models (Buser et al. ; Listgarten et al.…”

Section: Discussionsupporting

confidence: 85%

“…In terms of roughness the TiZr‐modMA and the Ti‐modMA presented similar Sa values (Liñares et al. ). Thus, surface topography may not be a reason for this finding.…”

Section: Discussionmentioning

confidence: 79%

“…The experimental model used in this study was described in a recent publication (Liñares et al. ). The ARRIVE recommendations (Kilkenny et al.…”

Section: Methodsmentioning

confidence: 99%

“…The present research group has shown in a recent preclinical study (Liñares et al. ) that clinical and histometric outcomes were similar for transgingival collar implant surface with acid etched structure and hydrophilic behavior in comparison to a machined collar surface The aim of the present investigation was to assess and compare the buccal soft tissue healing at implants with transgingival collar surface with acid etched structure and hydrophilic behavior to a machined one in terms of histometric outcomes, number of inflammatory cells, and collagen fiber orientation.…”

mentioning

confidence: 87%

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Soft tissue histomorphology at implants with a transmucosal modified surface. A study in minipigs

Liñares

Muñoz

Permuy

et al. 2014

Clinical Oral Implants Res

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Section: Discussionsupporting

confidence: 85%

“…In terms of roughness the TiZr‐modMA and the Ti‐modMA presented similar Sa values (Liñares et al. ). Thus, surface topography may not be a reason for this finding.…”

Section: Discussionmentioning

confidence: 79%

“…The experimental model used in this study was described in a recent publication (Liñares et al. ). The ARRIVE recommendations (Kilkenny et al.…”

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 87%

See 2 more Smart Citations

Soft tissue histomorphology at implants with a transmucosal modified surface. A study in minipigs

Liñares

Muñoz

Permuy

et al. 2014

Clinical Oral Implants Res

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“…A systematic review concluded that ‘ZrO 2 may have the potential to be a successful implant material', 32 while osseointegration of Ti alloys may be called similar to Ti depending in part on the surface modification applied and resulting surface morphology and hydrophobicity. 28,33,34 …”

Section: Introductionmentioning

confidence: 99%

Osteoblast integration of dental implant materials after challenge by sub-gingival pathogens: a co-culture study in vitro

et al. 2015

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Sub-gingival anaerobic pathogens can colonize an implant surface to compromise osseointegration of dental implants once the soft tissue seal around the neck of an implant is broken. In vitro evaluations of implant materials are usually done in monoculture studies involving either tissue integration or bacterial colonization. Co-culture models, in which tissue cells and bacteria battle simultaneously for estate on an implant surface, have been demonstrated to provide a better in vitro mimic of the clinical situation. Here we aim to compare the surface coverage by U2OS osteoblasts cells prior to and after challenge by two anaerobic sub-gingival pathogens in a co-culture model on differently modified titanium (Ti), titanium-zirconium (TiZr) alloys and zirconia surfaces. Monoculture studies with either U2OS osteoblasts or bacteria were also carried out and indicated significant differences in biofilm formation between the implant materials, but interactions with U2OS osteoblasts were favourable on all materials. Adhering U2OS osteoblasts cells, however, were significantly more displaced from differently modified Ti surfaces by challenging sub-gingival pathogens than from TiZr alloys and zirconia variants. Combined with previous work employing a co-culture model consisting of human gingival fibroblasts and supra-gingival oral bacteria, results point to a different material selection to stimulate the formation of a soft tissue seal as compared to preservation of osseointegration under the unsterile conditions of the oral cavity.

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Strategies for Optimizing the Soft Tissue Seal around Osseointegrated Implants

Abdallah

Badran

Ciobanu

et al. 2017

Adv Healthcare Materials

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Percutaneous and permucosal devices such as catheters, infusion pumps, orthopedic, and dental implants are commonly used in medical treatments. However, these useful devices breach the soft tissue barrier that protects the body from the outer environment, and thus increase bacterial infections resulting in morbidity and mortality. Such associated infections can be prevented if these devices are effectively integrated with the surrounding soft tissue, and thus creating a strong seal from the surrounding environment. However, so far, there are no percutaneous/permucosal medical devices able to prevent infection by achieving strong integration at the soft tissue-device interface. This review gives an insight into the current status of research into soft tissue-implant interface and the challenges associated with these interfaces. Biological soft/hard tissue interfaces may provide insights toward engineering better soft tissue interfaces around percutaneous devices. In this review, focus is put on the history and current findings as well as recent progress of the strategies aiming to develop a strong soft tissue seal around osseointegrated implants, such as orthopedic and dental implants.

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Peri‐implant soft tissues around implants with a modified neck surface. Part 1. Clinical and histometric outcomes: a pilot study in minipigs

Abstract: The soft tissue dimensions around all implant prototypes were similar and not affected by the implant surface modification.

Cited by 14 publications

References 36 publications

Soft tissue histomorphology at implants with a transmucosal modified surface. A study in minipigs

Soft tissue histomorphology at implants with a transmucosal modified surface. A study in minipigs

Osteoblast integration of dental implant materials after challenge by sub-gingival pathogens: a co-culture study in vitro

Strategies for Optimizing the Soft Tissue Seal around Osseointegrated Implants

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