Perianal Streptococcal Cellulitis: Treatment with Topical Mupirocin

Medina, Susana; Gómez, María Isabel Arias; Misa, Ricardo; Ledo, A.

doi:10.1159/000247453

Cited by 24 publications

(11 citation statements)

References 4 publications

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“…The clinical pattern is mainly defined by clearly marked perianal erythema. Itching, burning and soiling are typically reported [2][3][4][5][6][7][8][9][10]. The erythema can be associated with induration and even pain.…”

Section: Discussionmentioning

confidence: 99%

“…While children with PSD can be cured in almost all cases by eradication of Streptococci with systemic antibiotic treatment, we demonstrated that in adults, a substantial percentage of patients require continuing or further treatment of their concomitant anorectal disease in addition to treatment of PSD to achieve freedom from symptoms. Although topical antibiotic therapy with, e. g., erythromycin or mupirocin has been advocated for paediatric PSD by some authors in the past [3][4][5], most dermatologists and paediatrics will treat PSD by oral antibiotics.…”

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confidence: 99%

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Perianal streptococcal dermatitis in adults

Kahlke

Feeser²,

Jongen³

et al. 2018

coloproctology

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Perianal streptococcal dermatitis in adults

Kahlke

Feeser²,

Jongen³

et al. 2018

coloproctology

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“…Initially, the PID condition was described as “perianal cellulitis” in 1996 by Amren et al[2]; this term has since been used by other authors[10,14,28-31,38,56,59,61,63]. However, the term “cellulitis” was later considered inaccurate, since inflammation involves only the skin[4,20].…”

Section: Definitions and Terms Usedmentioning

confidence: 99%

Perianal infectious dermatitis: An underdiagnosed, unremitting and stubborn condition

Serban

2018

WJCP

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Perianal infectious dermatitis (PID) represents a superficial inflammation of the perianal skin, which is of bacterial origin (classically, group A beta-hemolytic streptococci). This narrative review aims to critically review and summarize the available scientific literature regarding pediatric PID, being the first of its kind, to the best of the author’s knowledge. It also reports the first cases of Romanian children with PID. Multiple databases were subjected to systematic literature search (from 1966 to April 30, 2018) to identify studies and case reports of children with PID. As such, this review provides updated information about essential aspects of PID (epidemiology, etiology, pathogenesis, as well as clinical features, required investigations and therapeutic options) and of diagnostic pitfalls. Although a well-defined entity, PID remains largely underdiagnosed. PID may mimic other common conditions with skin manifestations (like candidiasis, pinworms, eczema, irritant dermatitis, anal fissure, hemorrhoids, Crohn’s disease, psoriasis, seborrheic dermatitis, zinc deficiency dermatosis and even sexual abuse), with consequent unnecessary, sometimes expensive and invasive investigations and futile therapies, which cause patients and families discomfort and distress. Since PID has an unremitting course, early recognition is imperative, as it allows for prompt and efficacious antibiotic therapy. However, PID represents a stubborn condition and, even if properly treated, its recurrence rate remains high. Further well-designed prospective randomized controlled trials, with adequate follow-up, are required in order to formulate the optimum personalized antibiotic therapy (oral alone or in association with topical medication), able to prevent recurrences. Awareness of this condition by healthcare professionals should improve patient outcomes.

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“…So werden die Kinder neben einer perianalen Dermatitis, Juckreiz und Abb.1 ᭣ Scharf umrandetes, hellrot-feuchtes Erythem der Analhaut mit einer zirkulären Ausdehnung von 2,5 cm und dünnen Fibrin-/Eiterbelägen schmerzhafter Defäkation auch wegen Obstipation oder Blut im Stuhl vorgestellt [6,9,14]. So werden die Kinder neben einer perianalen Dermatitis, Juckreiz und Abb.1 ᭣ Scharf umrandetes, hellrot-feuchtes Erythem der Analhaut mit einer zirkulären Ausdehnung von 2,5 cm und dünnen Fibrin-/Eiterbelägen schmerzhafter Defäkation auch wegen Obstipation oder Blut im Stuhl vorgestellt [6,9,14].…”

Section: Differenzialdiagnosenunclassified

“…bis zur Symptomfreiheit andauern [6,8,12]. B. Mupirocin) diskutiert, da vereinzelt über eine Abheilung der Dermatitis darunter berichtet wird [9]. Zum Teil wird die Wirksamkeit lokaler Antibiotika (z.…”

Section: Therapie Und Verlaufunclassified

Streptokokkeninfektion als Ursache für eine chronische perianale Dermatitis bei Kindern

Lainka

Ballauff

2002

Monatsschr Kinderheilkd

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Perianal Streptococcal Cellulitis: Treatment with Topical Mupirocin

Cited by 24 publications

References 4 publications

Perianal streptococcal dermatitis in adults

Perianal streptococcal dermatitis in adults

Perianal infectious dermatitis: An underdiagnosed, unremitting and stubborn condition

Streptokokkeninfektion als Ursache für eine chronische perianale Dermatitis bei Kindern

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