Peribiliary Portal System in the Monkey Liver as Evidenced by the Injection Replica Scanning Electron Microscope Method

The Peribiliary Portal System in the Rabbit Liver

“…We could not, however, find any evidence for these views, but we believe that in the rabbit and also in the rat (see below) both the so-called "radicular portal veins" and "internal roots" represent the peribiliary portal system described by MURAKAMI et al (1974) in the monkey. Our previous study on the rat liver has shown the peribiliary plexuses as having both connections with the interlobular veins and with the hepatic sinusoids.…”

“…This view was supported by OLDS and STAFFORD (1930) in the cat and man. MURAKAMI et al (1974) also showed that the peribiliary plexus of the monkey was drained exclusively to the hepatic sinusoids and proposed to call this vascular 153 route from the peribiliary plexus to the hepatic sinusoids the peribiliary portal system.…”

Three‐dimensional visualization and physiologic evaluation of bile canaliculi in the rat liver slice by confocal laser scanning microscopy

“…There were significant differences between the BCF and ILHF at the respective measurement points between 3 and 40 min after the LY injection ( * p<0.05, * * p<0.01). Mean ILHF ILHF1 ILHF2 ILHF3 ILHF4 ILHF5 ILHF6 ILHF7 ILHF8 ILHF9 ILHF10 100 Previously, the morphology of the BC was evaluated using the dye injection method, biliary casts, or electron microscopy (Arias et al 1993, Elias and Sherrick 1969, Fawcett 1986, Jones and Spring-Mills 1988, Murakami et al 1974, Rappaport 1987. However, these previous studies only evaluated the morphology of the BC around the portal area.…”

“…The ductule epithelium exists in the ductules, which are involved in reabsorption and secretion of water and electrolytes (Sherlock and Dooley 1997). Although some studies reported the presence of BC epithelia (Gallin 1997, Ishii et al 1989, Roberts et al 1997, others did not (Arias et al 1993, Elias and Sherrick 1969, Fawcett 1986, Jones and SpringMills 1988, Murakami et al 1974, Rappaport 1987. Therefore, it remains unclear whether the BC is involved in secretion and/or reabsorption of bile salts, water, and electrolytes.…”

“…Previously, Murakami et al (1974), using electron microscopy, evaluated the morphology of the intralobular BC in biliary casts and demonstrated the reticular stereoscopic structure of Rappaport's zone 1 (Rappaport 1987) in the hepatic lobule (Arias et al 1993, Elias and Sherrick 1969, Fawcett 1986, Jones and Spring-Mills 1988, Murakami et al 1974, Rappaport 1987. However, the stereoscopic structure of other zones excluding zone 1, such as the central venous region (zone 3) and zone 2, remain unclear.…”