For more than a century, many concepts and several theories and principles pertaining to the goals, organization, methodology and evaluation of the effects of resistance training (RT) have been developed and discussed between coaches and scientists. This cumulative body of knowledge and practices has contributed substantially to the evolution of RT methodology. However, a detailed and rigorous examination of the existing literature reveals many inconsistencies that, unless resolved, could seriously hinder further progress in our field. The purpose of this review is to constructively expose, analyze and discuss a set of anomalies present in the current RT methodology, including: (a) the often inappropriate and misleading terminology used, (b) the need to clarify the aims of RT, (c) the very concept of maximal strength, (d) the control and monitoring of the resistance exercise dose, (e) the existing programming models and (f) the evaluation of training effects. A thorough and unbiased examination of these deficiencies could well lead to the adoption of a revised paradigm for RT. This new paradigm must guarantee a precise knowledge of the loads being applied, the effort they involve and their effects. To the best of our knowledge, currently this can only be achieved by monitoring repetition velocity during training. The main contribution of a velocity-based RT approach is that it provides the necessary information to know the actual training loads that induce a specific effect in each athlete. The correct adoption of this revised paradigm will provide coaches and strength and conditioning professionals with accurate and objective information concerning the applied load (relative load, level of effort and training effect). This knowledge is essential to make rational and informed decisions and to improve the training methodology itself.