This retrospective study explores the impact of comprehensive thermal insulation measures on the stress response of patients undergoing hysteroscopy surgery. A total of 600 patients who underwent hysteroscopy at our hospital from January 2018 to December 2022 were included. Participants were randomly assigned to an observation group (n = 305) and a control group (n = 295). The control group received standard nursing care, whereas the observation group received additional comprehensive thermal insulation measures. We compared body temperature and stress response indicators, including heart rate, diastolic blood pressure, systolic blood pressure, blood glucose, adrenaline, norepinephrine, and C-reactive protein, at 3 time points: before surgery (T0), 30 minutes into surgery (T1), and after surgery (T2). A comparative analysis of immune competence, focusing on the variations in CD3+, CD4+, CD8+ T lymphocyte populations, and CD4+/CD8+ ratios, was conducted between the groups preoperatively and at a 24-hour postoperative juncture. The occurrence of intraoperative complications after surgery was analyzed. The central body temperature in the observation group at T1 and T2 was higher than that of the control group (P < .001). The levels of heart rate, diastolic blood pressure, systolic blood pressure, blood glucose, adrenaline, norepinephrine, and C-reactive protein in the observation group at T1 and T2 were lower than those in the control group (P < .05). The percentage of CD3+, CD4+, CD4+/CD8+ cells in the observation group at 1 day after surgery was higher than those in the control group (P < .05). The incidence of intraoperative and postoperative complications in the observation group after surgery was lower than that in the control group (P < .001). Implementing a comprehensive thermal insulation protocol for patients undergoing hysteroscopy may help maintain core temperature and support immune response following surgery, potentially contributing to a smoother recovery process. Further research is warranted to confirm these findings and better understand the implications for patient care.
