Peripheral Neuroectodermal Tumour (Pnet) Lung Diagnosed by Fnac: A Rare Case Report

Abstract

We report a rare case of peripheral neuro-ectodermal tumor (PNET) in lung diagnosed by USG-guided FNAC in lung of a 19 year old male, who presented with cough, hemoptysis and pleuritic chest pain. CT chest showed a homogeneous mass in left posterior segment of lung with areas of necrosis. CT abdomen and bone scan studies were normal. Fine needle aspiration (FNA) revealed cellular smears comprised of small round blue cells arranged in rosettes, sheets, blue cells having fine chromatin, scant cytoplasm in an inflammatory background. Biopsy was advised for evaluation of small round blue cell to further typing and confirmation for further management. CTguided trucut biopsy revealed lesion with small round blue cells had round nuclei, fine chromatin with scant cytoplasm arranged in sheets, rosettes in thin fibrous septae. Immunohistochemistry (IHC) showed malignant cells were positive for CD 99, synaptophysin and chromogranin and negativity for CD45 and Cytokeratin.