PERK-mediated antioxidant response is key for pathogen persistence in ticks
Kristin L. Rosche,
Joanna Hurtado,
Elis A. Fisk
et al.
Abstract:A crucial phase in the life cycle of tick-borne pathogens is the time spent colonizing and persisting within the arthropod. Tick immunity is emerging as a key force shaping how transmissible pathogens interact with the vector. How pathogens remain in the tick despite immunological pressure remains unknown. In persistently infected
Ixodes scapularis
, we found that
Borrelia burgdorferi
(causative agent of Lyme disease) and
Anaplasma phagocytophilum
… Show more
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