Permacol in Eyelid Reconstruction — A Novel Use

Abstract

We feel it is a very good autologous graft substitute in eyelid reconstructive surgery and achieved satisfactory functional and aesthetic results.

Longevity results of modified Hughes procedure in reconstructing large lower eyelid defects

“… 1 , 2 Although, other studies considered that to leave the flap in place for 3 weeks prior to its separation is a drawback in the technique as it is not suitable for the patients with single eye or of amblyogenic age. 9 The problem has been addressed by many other investigators who reported that early division of the flap after 1–2 weeks comes with acceptable results and no complications. 2 , 10 , 11 …”

“…The overall cosmetic results of the procedure were satisfactory, and the esthetic outcome was favorable in most of the cases, which agreed with the results of other investigators. 7 – 9 …”

Recent Advances in Ophthalmic Plastic Surgery

“…Peter and Kumar 22 have used nonlayered Permacol to reconstruct the posterior lamina in combination with an advancement skin flap to reconstruct large defects of the lower eyelid. 22 Used as a scaffold, it eventually becomes vascularized and remodeled to reconstruct the eyelid. 22 Used as a scaffold, it eventually becomes vascularized and remodeled to reconstruct the eyelid.…”

“…Permacol is a relatively new biomaterial made from acellular cross-linked porcine dermal collagen with a structural architecture very similar to that of human dermis. 22 It is resistant to degradation by collagenase and is devoid of any material likely to elicit an allergic reaction. 22 It is resistant to degradation by collagenase and is devoid of any material likely to elicit an allergic reaction.…”

“…22 Used as a scaffold, it eventually becomes vascularized and remodeled to reconstruct the eyelid. 22 Decellularized bioengineered porcinederived membrane (Tarsys) has been successfully used as a spacer to reconstruct the retracted lower eyelid following extensive surgery and radiotherapy for a malignant tumor. 22 Decellularized bioengineered porcinederived membrane (Tarsys) has been successfully used as a spacer to reconstruct the retracted lower eyelid following extensive surgery and radiotherapy for a malignant tumor.…”