Permeability studies in a hypovolemic traumatic shock model: Comparison of ringer's lactate and albumin as volume replacement fluids

Redl, Heinz; Krösl, P.; Schlag, G.; Hammerschmidt, Dale E.

doi:10.1016/0300-9572(89)90081-6

Cited by 5 publications

(2 citation statements)

References 11 publications

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“…The mean arterial pressure varies between 20 and 55 mm Hg depending on the examiner and the species. This hypotensive shock state is maintained for 15 min, or in some studies for more than 3 h [53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76](table 3). …”

Section: Types Of Modelsmentioning

confidence: 99%

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Experimental Models of Hemorrhagic Shock: A Review

Fülöp

Turóczi²,

Garbaisz³

et al. 2013

Eur Surg Res

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Massive blood loss leading to hypovolemic shock is still a life-threatening situation. Recently, a great number of investigations have been conducted in order to understand the pathophysiological and immunological changes taking place during shock and to develop treatment strategies. These preclinical trials are based on animal studies. Although a wide spectrum of species and experimental models are available to researchers, it is rather difficult to create an ideal animal model to study hemorrhagic shock. A major challenge for investigators is the generation of a system which is simple, easily reproducible and standardized, while being an accurate replica of the clinical situation. The goal of this review is to summarize the current experimental models of hemorrhagic shock, highlighting their advantages and disadvantages to help researchers find the most appropriate model for their own experiments on hypovolemic shock.

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Section: Types Of Modelsmentioning

confidence: 99%

“…Most often, models combined with hemorrhagic shock and femur/tibia fracture are used for examination of this condition. Redl et al [72] created hind limb fracture in a fixed-pressure hemorrhagic dog model. They were able to draw useful conclusions related to a trauma-induced increase in lung water content.…”

Section: Types Of Modelsmentioning

confidence: 99%