Permeabilization surgery of the upper respiratory tract and its effects on sleep fragmentation and REM sleep

Abstract

Usually, patients with sleep disorders may complain of tiredness, fatigue, daytime sleepiness, difficulty in concentrating, and can reach up to falling asleep in inappropriate situations – condition known as the Pickwick syndrome. To avoid these unpleasant symptoms, a series of surgical procedures regarding the anatomical structures involved in sleep apnea were developed.The article is a general review regarding the sleep disorders and the influence of upper airways permeability on the quality of sleep and the sleep staging distribution. Also, we present some preliminary data obtained in a clinical study underwent in CESITO Centre “Sfanta Maria” Hospital, Bucharest, involving patients with sleep pathology that had polysomnographic evaluations before and after various surgical procedures of nasal and pharyngeal permeabilization.AIMS.To determine that permeabilization surgery of the upper airway tract may be used successfully in order to decrease the sleep fragmentation and increase the time of slow-wave sleep.CONCLUSION.6 months after the permeabilization surgery of the upper airway tract, the polysomnography reveals that the arousals index decreased and the sleep architecture undergoes changes that consist in decreasing the Stage 1 and Stage 2 sleep, therefore REM sleep reaches a better score.

Polysomnography outcomes on patients with obstructive sleep apnea after upper airways repermeabilization surgery

“…In a study published in 2017, we demonstrated the effect of the permeabilization surgery of the upper respiratory tract upon sleep fragmentation and REM sleep. The PSG performed 6 months after the surgical interventions revealed a decrease in the arousal index and a better REM sleep score (decrease of Stage 1 and Stage 2) 40 .…”