Permissive Hyperkapnie und Bauchlage – Therapiestrategien des ARDS

Abstract

Controlled mechanical hypoventilation with reduced tidal volumes and peak inspiratory pressures has been introduced into the treatment of ARDS in order to avoid pulmonary hyperinflation and ventilator-induced lung injury. The concomitant increase of arterial PCO 2 has been denoted as permissive hypercapnia. Recent clinical studies suggest a potential benefit of this concept for patients with acute respiratory failure, although several organ systems can be affected by the increase of PaCO 2 .