Persistent Fetal Haemoglobin and Falsely High Glycosylated Haemoglobin Levels

Abstract

This problem may be avoided by using a method that distinguishes between fetal and glycosylated haemoglobin or by testing glycosylation of hair or serum albumin if discrepancies arise. This is particularly important during pregnancy, when some women have an increase in fetal haemoglobin.

Fetal hemoglobin and hemoglobin A1c level among pediatric patients with type 1 diabetes

“…Our study was designed to evaluate a possible link between fetal hemoglobin and HbA1c measurement among pediatric patients with type 1 diabetes older than two years. It needs to be highlighted that in the study we also excluded children who were in diabetes remission phase (at least 1 year after diagnosis) to reduce this confounder which affects the HbA1c level and might interfere with HbA1c/HbF relationship (10)(11)(12). Additionally, we performed the serial measurements of both HbA1c and HbF.…”