“…As a testimony to their importance, aflatoxins have been the subject of numerous reviews in the past few years covering ecology , occurrence (Jelinek et al, 1989), detection (Pestka, 1986, l988), effects on human health (toxicity, carcinogenicity) (Bray & Ryan, 1991 ;Chang e t al., 1994;Chu, 1991 ; Dvorackova, 1990;Eaton & Gallagher, 1994), genetics (Bennett & Papa, 1988), biosynthesis Dutton, 1988) and compounds which affect biosynthesis , and control of aflatoxin contamination (Park e t al., 1988;Park & Liang, 1993;Bhatnagar e t al., 1995); (for general reviews see CAST, 1989;Ellis et al, 1991). Because of the difficulty in effectively and economically controlling aflatoxin contamination of food and feed by traditional agricultural methods (see below), recent efforts in several laboratories have focused on developing an indepth understanding of the molecular biology of the aflatoxin biosynthetic pathway.…”