Pet Imaging Studies in Drug Abuse Research

[18F]FDG brain uptake of C57Bl/6 male mice is affected by locomotor activity after cocaine use: A small animal positron emission tomography study

“…[ 18 F]FDG accumulates intensely in the myocardium and brain, as both are high glycolytic metabolic sites (Shreve et al, 1999). The brain glucose metabolism reflects in part the energy required for neurotransmission, so regional abnormalities in this process provide mechanistic information on specific neurotransmitters associated with these changes (Fowler et al, 1967). After the intake of a psychostimulant drug, such as cocaine, temporally limited function changes occur in the brain (Peña et al, 2015; Ungless et al, 2001; Xu et al, 2017).…”

Synergism and Antagonism of Influence Low Dose Radiation and Environment on Health of Population in Ukraine

“…We can not give a correct assessment of the role of these disorders in the pathogenesis of mental disorders. But, apparently, we can say that in the organism of such individuals there are grounds by which psychopathological manifestations arise [15][16][17]. Psychoemotional states of a healthy person and a patient with mental illnesses cannot be explained solely by physiological concepts.…”

Modulação da atividade encefálica pelo canabidiol em camundongos tratados com cocaína

“…[ 18 F]FDG accumulates intensely in the myocardium and brain, as both are high glycolytic metabolic sites . The brain glucose metabolism reflects in part the energy required for neurotransmission, so regional abnormalities in this process provide mechanistic information on specific neurotransmitters associated with these changes (Fowler et al, 1967). After the intake of a psychostimulant drug, such as cocaine, temporally limited function changes occur in the brain Ungless et al, 2001;Xu et al, 2017).…”