pH-responsive liposome-templated polyelectrolyte nanocapsules

Cuomo, Francesca; Lopez, Francesco; Ceglie, Andrea; Maiuro, Lucia; Miguel, Maria G.; Lindman, Björn

doi:10.1039/c2sm07388a

Cited by 62 publications

(47 citation statements)

References 41 publications

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“…Cuomo et al used liposomes as templates for polyelectrolyte LbL nanocapsules with rather small diameters. 268 LbL-assembling processes with negatively charged alginate and positively charged chitosan on liposome templates made of phosphatidylcholine and didodecyldimethylammonium bromide resulted in core shell nanoparticles. Liposomes made of phosphatidylcholine (65%) and didodecyldimethylammonium bromide (35%) and with diameters of 80 nm were used as LbL templates.…”

Section: Materials Aspectsmentioning

confidence: 99%

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

et al. 2013

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Materials fabrication with nanoscale structural precision based on bottom-up-type self-assembly has become more important in various current disciplines in chemistry including materials chemistry, organic chemistry, physical chemistry, analytical chemistry, biochemistry, colloid and surface chemistry, and supramolecular chemistry. Although the design of new materials based on nanoscale self-assembly is anticipated as a key concept, preparing complete three-dimensional structures at nanoscale precision remains a difficult target using current technologies. Rather, dimension-reduced approaches such as layering of two-dimensional nanostructures into precisely controlled lamellar nanomaterials are currently achievable. In particular, layer-by-layer (LbL) assembly is known as a highly versatile method for fabrication of controlled layered structures from various kinds of component materials using very simple, inexpensive, and rapid procedures. Therefore, fabrication of multilayer films through the LbL deposition process has attracted growing interest from various research communities. The high versatility and flexibility of LbL assembly is continuously creating new concepts, new materials, new procedures, and new applications. In this highlight review, we focus on nanoarchitectonics by LbL assembly. After an initial introduction on the invention and a brief history of the LbL assembly technique, innovations and the evolution of the technique are described based mainly on recent examples, which are categorized into two sections: (i) developments in methodology (technical, material, and phenomenological aspects with expansion of concept) and (ii) progress in applications (physical, chemical/biochemical, and biomedical applications).

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Section: Materials Aspectsmentioning

confidence: 99%

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

et al. 2013

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“…For example, ZnO nanoparticles were used for opening of microcapsules [77], while enhancement of release was observed upon incorporation of metal nanoparticles in polymeric shells. In this case the effectiveness of this process can be controlled by tuning the shell thickness and its roughness.…”

Section: Ultrasoundmentioning

confidence: 99%

Pharmacological aspects of release from microcapsules — from polymeric multilayers to lipid membranes

Wuytens

Parakhonskiy

Yashchenok

et al. 2014

Current Opinion in Pharmacology

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“…Shutava et al [48] suggested minimal permeability at pH 5.0-7.0 and maximal permeability at very high and very low pH capsules based on introducing tannic acid, a natural polyphenol, in PE assembly. Cuoma et al [50] demonstrated the role of alginate or chitosan as the outer layer at liposometemplated PE capsules: chitosan as outer layer is stable only at acidic pH, alginate as outer layer remains stable at all the pH 4.6 to 8. Cuoma et al [50] demonstrated the role of alginate or chitosan as the outer layer at liposometemplated PE capsules: chitosan as outer layer is stable only at acidic pH, alginate as outer layer remains stable at all the pH 4.6 to 8.…”

Section: Drug Deliverymentioning

confidence: 99%

How Can One Controllably Use of Natural ΔpH in Polyelectrolyte Multilayers?

Skorb

Möhwald

Andreeva

2016

Adv Materials Inter

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Most natural and synthetic polyelectrolytes (PEs) possess dissociable groups, and therefore the corresponding structures depend on pH. This enables manipulation of their properties, in special permeability, elasticity and swelling, and this can be made use of in many applications. The effect of individual polymer composition on the dissociation equilibrium is discussed. Different concentrations and pH values during the PE assembly affect concentration of charged groups per molecule on the dissociation equilibrium. Ionic strength also influences the protonation/deprotonation behavior of PE, that can be changed by adding different salt concentration but also varies with the concentration of charged groups in the polymer molecules. Electrostatic interactions of the polymer molecules strongly affect the dissociation equilibrium of weak PEs and, thus, layers architecture and properties that can be regulated by natural pH changes in such processes as self-healing, corrosion and antifouling, drug storage and delivery, etc

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pH-responsive liposome-templated polyelectrolyte nanocapsules

Cited by 62 publications

References 41 publications

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

Pharmacological aspects of release from microcapsules — from polymeric multilayers to lipid membranes

How Can One Controllably Use of Natural ΔpH in Polyelectrolyte Multilayers?

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