Pharmacist adscription to intensive care: Generating synergies

Sereno, María; Serrano, Rosario Mérida; Díaz-Miguel, R. Ortiz; González, Mercedes Catalán; Álvarez, H. Abdel-Hadi; Checa, A. Ambrós; Martı́nez, Mercedes

doi:10.1016/j.medine.2018.02.005

Cited by 2 publications

(2 citation statements)

References 18 publications

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“…The optimisation of administration schedules might be irrelevant because numerous medications were used in intensive care units (ICUs) (9). Pharmacist intervention is also significant to improve safety particularly in ICUs (Franco Sereno et al, 2018). These three things should be used along with the approaches, which would be discussed below.…”

Section: Resultsmentioning

confidence: 99%

Management of Y-Site Incompatibility of Intravenous Medication: A Systematic Review

2022

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Patients in intensive care units have a critical problem with Intravenous (IC) drug administration. The effort to decrease incompatibility or manage the incompatibility risks is paramount significant to reduce morbidity and mortality. This review collates all published studies about kinds of approaches to prevent or solve y-site incompatibility, evaluate the effectiveness of those approaches, and provide the recommendation. A scoping review was conducted in PUBMED in a time frame 1 Januari 2010- 28 February 2021. All type studies of randomised controlled trials, observational studies, before and after studies, also review articled were considered to include. We identified 944 studies; of these, 78 met the inclusion criteria, but 44 were excluded. A total 34 articles were included in the analyses. Six articles reported protocol, two-dimensional chart, database, or pH colour code to provide information of incompatibilities. Two-dimensional chart and pH code were comparable with a gold standard. Specific protocol markedly reduced the incompatibility event. Normal saline (NS) flushing effectively prolonged patency and reduced the incompatibility rate. NS was preferred over heparin associated with thrombocytopenia. In-line filtration has been proved to reduce particulate matter, as well as the precipitation, resulted from incompatibility. The filter also reduced inflammation, infection, and complication appreciably. Four studies used more than three lumen catheters which successfully decrease the number of precipitation and incompatibility events. Therefore, separating incompatible drugs using multi-lumens according to the chart should be preferred. However, when co-administration is inevitable, flushing or filter is needed.

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Section: Resultsmentioning

confidence: 99%

Management of Y-Site Incompatibility of Intravenous Medication: A Systematic Review

2022

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“…Similar results were described in the studies from Sereno et al (33 %) and Fidelis et al (52.7 %). (11,24) In clinical practice, it is observed that antimicrobial doses are extremely important in the management of infections in critically ill patients, especially in cases of sepsis and septic shock. Moreover, other factors, such as obesity, positive fluid balance, renal and/or hepatic failure are quite common and require frequent dosage adjustment, with daily monitoring, to avoid clinical worsening, emergence of toxicity or increased microbial resistance.…”

Section: Discussionmentioning

confidence: 99%

Intervenciones farmacéuticas y factores asociados a su aceptación en unidades de cuidados intensivos en Brasil

et al. 2023

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Objetivo: El propósito de este estudio es evaluar las intervenciones farmacéuticas (IF) realizadas sobre PRM y los factores asociados a su aceptación. Método: Se trata de un estudio descriptivo y transversal que analizó las IF realizadas a pacientes adultos de dos UCI de Fortaleza, Brasil, en 2019. Las IF se analizaron en las categorías cantidad de fármaco y estrategia farmacológica, utilizando la clasificación propuesta por Sabater et al. Los fármacos se clasificaron además por el Sistema de Clasificación Anatómica, Terapéutica, Química y por la clasificación de Fármacos de Alta Vigilancia (FAV). Resultados: Se incluyeron 305 pacientes, siendo la mayoría del sexo masculino (55,1 %), ancianos (52,8 %) y atendidos en la UCI quirúrgica (51,4 %). Se analizaron 1.317 IF y se aceptaron el 88,0 %, siendo la sustitución de uno o más fármacos (28,0 %) y la adición de uno o más fármacos (27,7 %) las más frecuentes. La clase terapéutica más prevalente fue antiinfeccioso de uso sistémico (24,1 %) y los FAV estuvieron implicados en el 21,7 % de las IF. Se observó asociación entre las IF aceptadas e ingreso en UCI clínica (p<0,0001), FAV (p=0,0013), sustitución de uno o más fármacos (p=0,0062) y la clase sustitutos sanguíneos y soluciones de perfusión (p= 0,0187). Conclusiones: Se realizaron y aceptaron un elevado número de IF, lo que refuerza la importancia del farmacéutico en la revisión de las prescripciones médicas en UCI.

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Pharmacist adscription to intensive care: Generating synergies

Cited by 2 publications

References 18 publications

Management of Y-Site Incompatibility of Intravenous Medication: A Systematic Review

Management of Y-Site Incompatibility of Intravenous Medication: A Systematic Review

Intervenciones farmacéuticas y factores asociados a su aceptación en unidades de cuidados intensivos en Brasil

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