Pharmacological Interventions to Prevent the Need for Blood and Blood Component Therapies:

Abstract

Pharmacological Interventions to Prevent the Need for Blood and Blood Component Therapies:Protease Inhibitor or Lysine Analogue?he first question to address is why the concern about transfusions in major surgery. The presence of transmissible agents in transfused blood and blood products is an obvious concern. Of more immediate concern are data showing that the transfusion of red cells contributes significantly to patient morbidity and mortality. The mechanism of action responsible is thought to be an immunomodulator mechanism.