Pharmacological studies on antidiarrheal effects of berberine and Geranii Herba.

Berberine as a potential autophagy modulator

“…Berberine (Brb; Figure ) is a yellowish isoquinoline alkaloid (Mirhadi, Rezaee, & Malaekeh‐Nikouei, ), which is present at different levels in the roots, rhizomes, and the stem bark of plants such as Berberis aristana , Berberis vulgaris , Berberis petiolaris , Berberis aquifolium , Berberis asiatica , Berberis thunbergii , Coptis teeta , Coptis chinesis , Hydrastis canadensis , Phellodendron amurense , and Caulis mahiniae (Imanshahidi & Hosseinzadeh, ; Singh & Mahajan, ; Tabeshpour, Imenshahidi, & Hosseinzadeh, ). Brb is considered as a herbal with diverse medical potential, such as antimicrobial (Tillhon, Guamán ortiz, Lombardi, & Scovassi, ), antiviral (Takase, Yamamoto, Ito, & Yumioka, ), antidiarrheal, antipyretic, and anti‐inflammatory (McCubrey et al, ; Neag et al, ), and the ability to diminishing dyslipidemia (Sahebkar & Watts, ), and liver fibrosis (Feng et al, ). It also has protective effects on congestive heart failure, cardiac arrhythmia, and hypertension (Xue et al, ).…”