Pharmacotherapy for vertigo: a current perspective

Swain, Santosh Kumar

doi:10.18203/issn.2454-5929.ijohns20202806

Cited by 8 publications

(6 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, pharmacological treatments have been associated with side effects in up to 16.9% of participants, including sedation, drowsiness and dizziness. [24][25][26][27][28] Further, while pharmacological treatments may alleviate concussive symptoms, research suggests such interventions may mask underlying neural dysfunction, 15 delay central compensatory mechanisms and contribute to delayed recovery. 10 Non-pharmacological interventions are therefore recommended commonly.…”

Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

Effectiveness of non-pharmacological treatments for vestibular and oculomotor dysfunction in patients with persistent post-concussive symptoms: protocol for a systematic review and meta-analysis

et al. 2023

View full text Add to dashboard Cite

IntroductionConcussion is a form of mild traumatic brain injury that disrupts brain function. Although symptoms are mostly transient, recovery can be delayed and result in persistent postconcussive symptoms (PPCS). Vestibular and oculomotor dysfunction are among the most debilitating impairments associated with PPCS. However, pharmacological interventions for these impairments are associated with deleterious side effects. Accordingly, increasing research has examined the utility of non-pharmacological interventions for PPCS. The aim of this review is to synthesise and evaluate the effectiveness of non-pharmacological interventions for the treatment of vestibular and oculomotor dysfunction for patients with PPCS.Methods and analysisSystematic searches of MEDLINE, PubMed, Web of Science and Scopus will identify randomised controlled trials employing non-pharmacological treatments for vestibular and/or oculomotor dysfunction for PPCS. Such interventions may include, but are not limited to, vestibular rehabilitation, optokinetic stimulation and vestibulo-ocular reflex exercises. Assessments of oculomotor function will include versional eye movements, vergence eye movements, visual-fixation movements and accommodation response. Assessments of vestibular function will include the Fukuda Step test, functional balance tests, force displacement tests, and subjective reports of balance disruption or vertigo. Where appropriate, meta-analyses of standardised mean differences will be conducted using a random effects model for continuous outcomes. For dichotomous outcomes (improved vs not improved following treatment), effects will be expressed as relative risk. The impact of heterogeneity will be calculated using the I2statistic. The Physiotherapy Evidence Database scale will be used to determine the methodological quality of individual studies and Grading of Recommendations, Assessment, Development and Evaluations used to assess the certainty and quality of evidence for each outcome.Ethics and disseminationEthical approval is not required for this review. Findings will be disseminated through peer-reviewed publications and conference presentations.PROSPERO registration numberCRD42021254720.

show abstract

Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

Effectiveness of non-pharmacological treatments for vestibular and oculomotor dysfunction in patients with persistent post-concussive symptoms: protocol for a systematic review and meta-analysis

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Vestibular sedatives can be prescribed for reducing the acute onset vertigo after cochlear implantation. 44 In this situation, the interaction between vestibular and visual systems plays an important role. Visual stimuli are usually able to suppress the vestibular afferences by inactivating the paretio-insular vestibular cortex, so stabilizes the equilibrium performance.…”

Section: Treatmentmentioning

confidence: 99%

Vertigo following cochlear implantation: a review

Swain

2022

Int J Res Med Sci

Self Cite

View full text Add to dashboard Cite

Cochlear implantation may cause a detrimental effect on vestibular function and residual hearing. A significant number of patients with a cochlear implant present with vertigo. There are several mechanisms for dizziness following cochlear implantations. The causes may be surgical trauma, disruption of normal cochlear physiology, or ensuing endolymphatic hydrops. Vibratory trauma affecting the cochlea during cochleostomy plays a vital role in causing paroxysmal vertigo in patients with a cochlear implant. In addition, the vibrations affecting the cochlea are enough to dislodge otoconia particles. During cochlear implantation, it is necessary to insert an electrode array into the cochlea and thus the chance of damage to cochlear and function may happen. Dizziness or vertigo may develop after cochlear implantation. It usually occurs due to vestibular hypofunction. Vertigo following cochlear implantation has not frequently been documented in the literature previously. However, the increasing number of cochlear implantations in the current scenario is showing different postoperative complications like vestibular symptoms among patients with an implant. The vestibular symptoms following cochlear implantation range from a gradual sense of mild unsteadiness or lightheadedness to brief attacks of whirling vertigo. Vertigo following cochlear implantations affects the quality of life although vestibular therapy is often helpful to manage this condition. The article aims to provide a comprehensive review of vertigo following cochlear implantation.

show abstract

“…The delayed diagnosis of BPPV in children can lead to attention and behavior impairment. 44 The treatment is based on the use of the Epley's or Semont's maneuver for posterior semicircular canal BPPV and the Gufoni maneuver for horizontal semicircular canal BPPV. 45 The Epley maneuver is one of the most effective CRP for the treatment of the posterior canal BPPV.…”

Section: Treatmentmentioning

confidence: 99%

Benign paroxysmal positional vertigo in pediatric age group: a review

Swain

2022

Int J Contemp Pediatr

Self Cite

View full text Add to dashboard Cite

Vertigo is not common in the pediatric age group, but probably more often than was formerly thought. Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo. It consists of the short duration of vertigo attacks found in a definite head position. The exact cause of BPPV is related to the idiopathic detachment of otoconia from the utricular membrane. The prevalence of BPPV in children is lower than in the adult age group. In children with BPPV, the symptoms consist of transitory rotational vertigo and torsional/ vertical/ horizontal or mixed nystagmus, depending on the position of the intra-labyrinthine otoliths, with latency and intensity in a typical crescendo-decrescendo pattern and it is exhaustible, reversible and fatiguing similar to adults. The diagnosis of BPPV can be accurately done by taking a detailed medical history, audiogram, and by use of positional testing. In children, BPPV can be successfully diagnosed and treated. In most cases, pediatric patients could not express details of their symptoms, and clinicians cannot always obtain adequate medical histories and determine their objective signs. So, it is not easy to study the BPPV in children. There are only a few articles describing BPPV in the pediatric age group, and therefore this subject is not well known to most otolaryngologists and clinicians. This review article discusses the epidemiology, etiopathology, clinical manifestations, diagnosis, and treatment of BPPB in the pediatric age group.

show abstract

Pharmacotherapy for vertigo: a current perspective

Cited by 8 publications

References 19 publications

Effectiveness of non-pharmacological treatments for vestibular and oculomotor dysfunction in patients with persistent post-concussive symptoms: protocol for a systematic review and meta-analysis

Effectiveness of non-pharmacological treatments for vestibular and oculomotor dysfunction in patients with persistent post-concussive symptoms: protocol for a systematic review and meta-analysis

Vertigo following cochlear implantation: a review

Benign paroxysmal positional vertigo in pediatric age group: a review

Contact Info

Product

Resources

About