Pharyngeal leiomyosarcoma

A Case of Hypopharyngeal Leiomyosarcoma

“…The presenting symptoms vary widely and include hoarseness [3,5], dysphagia [3], pyrexia of unknown origin, weight loss, feeling of 'something in the throat' [2], hypernasality and nasal regurgitation [4], difficulty and pain when swallowing [6,7] and dyspnea, as noted in our case. However, these symptoms and signs are not specific, as hoarseness and difficulty in swallowing occur in other lesions including benign leiomyoma of the hypopharynx [14].…”

“…The second case of a 55-year-old man with leiomyosarcoma of the postcricoid region was reported in 1970 by Mankodi et al [3]. Glover and Park [4], Watanabe [5], Tommerup et al [6] and Mineta et al [7] reported leiomyosarcomas of the posterior hypopharyngeal wall, arytenoid region and posterior hypopharyngeal wall, respectively.…”

Leiomyosarcoma of the tonsil

“…12 Another patient with tumour arising from the posterior pharyngeal wall presented with symptoms of dysphagia and hypernasal speech. 13 Two further cases of pharyngeal leiomyosarcoma have been described, but their exact site was unknown. 14, 15 The differential diagnosis of leiomyosarcoma includes leiomyoma, malignant melanoma, spindle cell SCC and sarcoma.…”

The Histology of Borderline Cancer

“…Since then, at least a further six accounts have appeared (Hay-Roe et al , 1960;Sherwin et al , 1963;Hughes and Cruiekshank, 1969;Razzuk et al, 1971;Shields et al, 1972;Enrile et al, 1973). A further single example of what is certainly the same lesion was described by Glover and Park (1971) but, in error (Park, 1979), as a pharyngeal leiomyosarcoma (local Case 8.6).…”

“…Examination showed a smooth globular mass, 30 X 30 X 15 mm, in the hypopharynx. This lesion was the subject of a case report (Glover and Park, 1971) when it was described and designated a 'leiomyosarcoma'. Subsequent events showed that this diagnosis was almost certainly wrong; or, at least, that the mass was in retrospect identical with the lesion described earlier, and later by others, for example Sherwin and colleagues ( 1963) and Enrile and associates (1973), as a polypoid pseudo-sarcomatous carcinoma.…”