2018
DOI: 10.1016/j.athoracsur.2017.08.013
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Phase 1 Trial Evaluating Safety of Pulmonary Artery Sealing With Ultrasonic Energy in VATS Lobectomy

Abstract: PA branch sealing for vessels 7 mm or less was safely achieved using an ultrasonic energy vessel-sealing device in VATS lobectomy. Large-scale, prospective, multi-institutional studies are necessary before widespread clinical application of energy for PA branch sealing in VATS lobectomy.

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Cited by 13 publications
(12 citation statements)
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“…9 Two phase 1 trials evaluated the safety of ultrasonic energy for PA sealing in open and VATS lobectomy. 10,11 These 2 trials allowed us to obtain safety data to support the current phase 2 multicenter trial.…”
Section: Discussionmentioning
confidence: 99%
“…9 Two phase 1 trials evaluated the safety of ultrasonic energy for PA sealing in open and VATS lobectomy. 10,11 These 2 trials allowed us to obtain safety data to support the current phase 2 multicenter trial.…”
Section: Discussionmentioning
confidence: 99%
“…These results could be explained by the mechanical principles underlying the two techniques. In contrast to electrocautery sealing by heat coagulation only, the Harmonic ACE Plus® combines heating and instrument blades mechanical pressure, fusing vessels walls and producing a permanent seal for vessels up to 5 mm [3][4][5][6][7][8]14,16,18,19]. This sealing ability should prevent any oozing or lymphatic leak.…”
Section: Discussionmentioning
confidence: 99%
“…Focusing on VATS lung lobectomy and lymphadenectomy, energy tools such as electric hook (monopolar energy), Harmonic ACE Plus® (ultrasound energy), LigaSure™ (bipolar energy) and Enseal® (bipolar energy), are commonly used during pleural adhesiolysis, hilar dissection, small vessel sealing and lymph node removal [1][2][3][4][5][6][7][8][9][10]. However, to date the available information are insu cient to establish the superiority of any of these devices in enhancing the postoperative course after this type of procedure [4][5][6].…”
Section: Introductionmentioning
confidence: 99%
“…Focusing on VATS lung lobectomy and lymphadenectomy, energy tools such as electric hook (monopolar energy), Harmonic ACE Plus® (ultrasound energy), LigaSure™ (bipolar energy), Enseal® (bipolar energy) and Thunderbeat® (ultrasound energy+ bipolar energy) are commonly used during pleural adhesiolysis, hilar dissection, small vessel sealing and lymph node removal [1][2][3][4][5][6][7][8][9][10]. However, to date the available information is insufficient to establish the superiority of any of these devices in enhancing the postoperative course after this type of procedure [4][5][6].…”
Section: Introductionmentioning
confidence: 99%