Phase II Study of Limited Surgery for Early Gastric Cancer: Segmental Gastric Resection

Abstract

Compared with distal gastrectomy, SR for EGC of the middle stomach decreased the surgical risk and postoperative complications without increasing the recurrence rate.

Limited subtotal gastrectomy for early remnant gastric cancer

“…Previous studies have presented the clinical and histopathological features of RGC, and SG was partly carried out in some cases [13][14][15][16]. Although limited surgery such as segmental gastrectomy for primary early gastric cancer has often been reported [17][18][19][20][21], there have been no reports about limited surgery for ERGC. In our institution, endoscopic treatment for RGC is indicated for intramucosal cancer with no lymph node metastasis, which is confirmed as well or moderately differentiated adenocarcinoma.…”

“…We adopted the SG for ERGC with the concept of distal gastrectomy after anterectomy. Although several authors have reported better outcomes after less invasive surgery for primary gastric cancer [17][18][19][20][21], there have been no reports on limited surgery for RGC. This study is believed to be the first on less invasive surgery for RGC.…”

Factors for Postoperative Gallstone Occurrence in Patients with Gastric Cancer: a Meta-analysis

“…According to the inclusion and exclusion criteria, we rejected the literature which didn't fit criterion, then 15 literatures (Mizuta et al, 1990;Pezzolla et al, 1993;Kodama et al, 1995;Wu et al, 1995;Hidetoshi et al, 1998;Furukawa et al, 1999;Shibata et al, 2004;Tomita et al, 2004;Akatsu et al, 2005;Kobayashi et al, 2005;Yoo et al, 2005;Nunobe et al, 2007;Kojima et al, 2008;Fukagawa et al, 2009;Sun et al, 2011) were included into this study, including 3 RCT articles, 5 cohort study articles and 7 case-control study articles. The number of cases is from 32 to 893 in the 15 articles.…”

“…We made grouping based on whether reserving vagus nerve, including one RCT study (Sun et al, 2011), two cohort studies (Furukawa et al, 1999;Tomita et al, 2004) and two case-control studies (Hidetoshi et al, 1999;Kojima et al, 2008) (Figure 4). The heterogeneity test was (P=0.78, I 2 =0%), indicating that the homogeneity was good, then we analyzed the studies with fixed effect model, the pooled OR [95%CI] was 0.13 [0.05, 0.33], and the combined effect size had statistically significant (P<0.0001).…”

The role of surgery in the current treatment of gastric carcinoma

“…Among patients who underwent distal gastrectomy, postsurgical complications (anastomotic failure, stenosis, infection, and pancreatic fistula) were observed in 7 patients (14%) and cholelithiasis in 8 patients (16%). In the group treated with segmental gastrectomy, postoperative complication and cholelithiasis were each observed in 1 patient (2%), and the incidences were significantly lower in this group (P Ͻ 0.05) [12].…”