Phenolic acid bound arabinoxylans extracted from Little and Kodo millets modulate immune system mediators and pathways in RAW 264.7 cells

Srinivasan, Aswini; Aruldhas, Jenifer; Perumal, Senthamil Selvan; Ekambaram, Sanmuga Priya

doi:10.1111/jfbc.13563

Cited by 10 publications

(3 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of the research by Liu et al [11] reported that corn stalk, xylan, and lignin had a peak at 1043 cm -1 related to C-O, C-C stretching, and glycosidic bonds (C-O-C) according to Srinivasan et al [19]. In this research, the glycosidic bonds in xylan were detected from 1041 and 1043 cm -1 peaks, which experienced a slight shift from corncob at 1038 cm -1 .…”

Section: Fourier Transform Infra Red (Ft-ir)mentioning

confidence: 49%

The Properties of Xylan Extracted from Corncob Using Deep Eutectic Solvent

Agustinisari,

Herawati,

Widaningrum

et al. 2024

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

Corncob is an abundant agricultural biomass that is generally underutilized and discarded. It has potential to be a resource for high-value products due to its cellulose and hemicellulose content. Xylan, which is the primary constituent of hemicellulose, can serve as a raw material or intermediary in both non-food and food industry. This research aims to study the extraction of xylan from corncob using deep eutectic solvent (DES) for clean processing and analyzes the characteristics of corncob xylan. DES comprises choline chloride and acetic acid with a molar ratio of 1:2. Xylan was extracted from corncobs by immersion in aqueous DES (70% and 90%) and heating using an autoclave at 105°C for 15 minutes. FT-IR and NMR characterized the chemical structures of xylan, while FE-SEM observed the surface. The FT-IR result showed that xylan had a peak range of 1041 cm−1, which is attributed to the glycosidic bond. A delignification process seems to have occurred as indicated by the absorption peak at 1475-1477 cm−1, indicating the presence of lignin in xylan and solid residue. Both types of extracted xylan had similar NMR spectra in the 3-4.3 ppm range, which indicates that they contained xylose. The solid residue structure obtained from extracting two DES concentrations shows the difference in the extraction process. However, the surface morphology of the two types of extracted xylan had a similar irregular shape and roughness. The use of the DES choline chloride-acetic acid could lead to the extraction and separation of xylan from lignocellulosic corncob.

show abstract

Section: Fourier Transform Infra Red (Ft-ir)mentioning

confidence: 49%

The Properties of Xylan Extracted from Corncob Using Deep Eutectic Solvent

Agustinisari,

Herawati,

Widaningrum

et al. 2024

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

show abstract

“…Soluble dietary fibers, including β-1,3/1,4 glucan, water-soluble AX, and arabinogalactan protein, have low binding to phenolics (10%), whereas insoluble dietary fibers such as water-insoluble AX and cellulose-lignin complexes have high binding to phenolic acids (90%) [53]. The total phenolic acid content of WUAX obtained by Srinivasan et al, (2020Srinivasan et al, ( & 2019 from alkali extracts of four millet varieties was 104.3, 164.6, 345.5, and 1307.7 μg/g, respectively, all containing p-coumaric acid and ferulic acid, with ferulic acid being the most represented, suggesting that the phenolic acid content of AX is highly correlated with genotype in addition to structure and extraction method [54,55].…”

Section: Combination Of Phenolic Compoundsmentioning

confidence: 99%

Cereal-Derived Water-Unextractable Arabinoxylans: Structure Feature, Effects on Baking Products and Human Health

Huang,

Baia,

Buccato

et al. 2024

Preprint

View full text Add to dashboard Cite

Arabinoxylans (AXs) are non-starch polysaccharides with complex structures naturally occurring in grains (i.e., barley, corn, and others) providing many health benefits, especially as prebiotics. AXs can be classified as water-extractable (WEAX) and water-unextractable (WUAX) based on their solubility, with properties influenced by grain sources and extraction methods. A large body of evidence shows that AXs exert an im-portant health impact, including glucose and lipid metabolism regulation and immune system enhancement, which is induced by the interactions between AXs and the gut microbiota. Recent research underscores the dependence of AX physiological effects on structure, advocating for a deeper understanding of struc-ture-activity relationships. While systematic studies on WEAX are prevalent, knowledge gaps persist re-garding WUAX, despite its higher grain abundance. Thus, this review reports recent data on WUAX struc-tural properties (chemical structure, branching, MW) in cereals under different treatments. It discusses WUAX applications in baking and its benefits deriving from gut fermentation.

show abstract

“…There are also reports on immunostimulant and immunomodulatory responses in little and kodo millet, respectively, in RAW 264.7 cells [9]. Apart from all these bioactive compounds and health promoting affects, P. scrobiculatum is involved in causing intoxication and poisoning by fungal pathogens in moist and humid conditions.…”

Section: Introductionmentioning

confidence: 99%

"Potential Risk of Cyclopiazonic Acid Toxicity in Kodua Poisoning"

Bhanu LS

2023

BJSTR

View full text Add to dashboard Cite

Kodo millet (Paspalum scrobiculatum L.) is minor millet extensively nutritious and is used as a staple food in some parts of North India. Although millet is cultivated in dry and semi-arid regions, sometimes environmental conditions like spring and summer strike as being suitable for a certain kind of poisoning which leads to greater economic crop loss. Millets are more prone to fungal infection followed by bacterial and viral; these infections adversely affect the grain and fodder yield. Ergot is a parasitic fungal endophyte that grows in the ear heads of various blades grass, most frequently on kodo millet, consumption of such Kodo grains is often found to cause poisoning. The grains of kodo millet are frequently infested with Aspergillus and penicillum, which produces a considerable amount of a mycotoxin, cyclopiazonic acid (CPA). This review reveals the fungal pathogens associated with the secretion of CPA and its toxicity on animals and humans, both by itself or in combination with other mycotoxins, and its biocontrol strategies employed to overcome the production of mycotoxin and storage methods to be practiced after the postharvest of kodo grains for better utilization.

show abstract

Phenolic acid bound arabinoxylans extracted from Little and Kodo millets modulate immune system mediators and pathways in RAW 264.7 cells

Cited by 10 publications

References 36 publications

The Properties of Xylan Extracted from Corncob Using Deep Eutectic Solvent

The Properties of Xylan Extracted from Corncob Using Deep Eutectic Solvent

Cereal-Derived Water-Unextractable Arabinoxylans: Structure Feature, Effects on Baking Products and Human Health

"Potential Risk of Cyclopiazonic Acid Toxicity in Kodua Poisoning"

Contact Info

Product

Resources

About