Phenolic acid content, antioxidant properties, and antibacterial potential of flowers and fruits from selected Pakistani indigenous medicinal plants

Naqvi, Syed Ali Raza; Waseem, Rifaqat; Mahmood, Nasir; Hussain, Zaib; Khan, Zulfiqar Ali; Shahzad, Sohail Anjum; Yar, Muhammad; Amin, Rashid; Bukhari, Shazia Anwer; Zahoor, Ameer Fawad; Javed, Sadia; Hussain, Abdullah Ijaz

doi:10.2306/scienceasia1513-1874.2013.39.340

Cited by 10 publications

(4 citation statements)

References 24 publications

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“…TPC was determined using a modified Folin-Ciocalteu method [ 30 ]. Briefly, 1 mL of plant extract was mixed with 1 mL of Folin-Ciocalteu reagent and allowed to react at room temperature for 5 min, then 5 mL of Na 2 CO 3 (1 M) was added.…”

Section: Methodsmentioning

confidence: 99%

Phytochemicals, Health-Promoting Effects, and Enzyme Inhibition Traits of Phlomis stewartii Extracts

Rasheed,

Naqvi,

Al-Asmari

et al. 2024

Molecules

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Phlomis stewartii is a wild, perennial woody plant used for diverse therapeutic targets. The present work evaluated the influence of independent variables such as extraction time, solvent concentration, and speed in the range of (100 mL, 150 mL, and 200 mL), (2 h, 5 h, and 8 h), and (100 rpm, 150 rpm, and 200 rpm), respectively, on extraction yields, phytochemical components, total phenolic contents (TPC), and total flavonoid contents (TFC) of P. stewartii extract. In the present work, response surface methodology (RSM) was applied to optimize the extraction yield. High-performance liquid chromatography (HPLC) was performed to detect the bioactive constituents of the extracts. The potent extracts were analyzed to study α-amylase and α-glucosidase inhibitory activities. Under the optimized conditions of solvent concentration (200 mL), extraction time (8 h), and speed (150 rpm), the whole plant methanol extract (WPME) showed a maximum extraction yield of 13.5%, while the leaves methanol extract (LME) showed a maximum TPC of 19.5 ± 44 mg of gallic acid equivalent (GAE) per gram of extract and a maximum TFC of 4.78 ± 0.34 mg of quercetin equivalent (QE) per gram of extract. HPLC analysis showed the presence of p-coumaric, gallic acid, quercetin, salicylic acid, sinapic acid, and vanillic acid. LME showed the highest α-amylase inhibitory activity (IC50 = 46.86 ± 0.21 µg/mL) and α-glucosidase inhibitory activity (IC50 value of 45.81 ± 0.17 µg/mL). Therefore, in conclusion, LME could be considered to fix the α-amylase and α-glucosidase-mediated disorders in the human body to develop herbal phytomedicine.

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Section: Methodsmentioning

confidence: 99%

Phytochemicals, Health-Promoting Effects, and Enzyme Inhibition Traits of Phlomis stewartii Extracts

Rasheed,

Naqvi,

Al-Asmari

et al. 2024

Molecules

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“…C. album's antibacterial activity against S. aureus (ATCC25923) and E. coli (ATCC25922) was tested using agar well diffusion [22]. These bacterial strains were incubated at 37 • C for 24 h. After dissolving 1.38 g of Mueller-Hinton agar in 60 mL of water, the mixture was heated to boiling.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Evaluation of Anti-Infection and Anti-Diabetic Activities in Methanolic and n-Hexane Plant Extracts of Indigenously Cultivated Chenopodium album

Hussain,

Janjua,

Haq

et al. 2024

Agronomy

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The Asian region of earth has a rich agriculture system that provides extensive opportunities to boost pharmaceutical and nutritional research to address the use of food crops for health benefits and potential clinical applications. The traditionally cropped green leaf vegetable indigenously known as Bathu and botanically known as Chenopodium album (C. album) is traditionally used as a sedative, blood purifier, hepatoprotectant, diuretic, and antiscorbutic laxative. In this study, we investigated the anti-infection potential, anti-diabetic potential, and mineral composition of indigenously cultivated C. album plant extracts. Methanol and n-hexane solvents were used to extract phytochemicals at different extraction conditions. The maximum yield of 12.72 ± 0.36 g/100 g extract was obtained in methanol with 200 rpm shaking, 200 mL solvent, and an 8 h extraction period. Under the same conditions, n-hexane gave 2.09 ± 0.29 g/100 g extract. Good alpha-amylase inhibition efficiency was shown by the n-hexane extracts, while the methanol extracts showed good urease inhibition potential. The H6 extract had the lowest IC50 (8.16 ± 0.2 ug/mL) as compared to the standard acarbose (9.27 ± 0.6 ug/mL). Similarly, the M6 extract revealed a significant urease inhibitory potential, i.e., IC50 of 18.77 ± 0.6 ug/mL, which was close to the standard thiourea (IC50: 19.09 ± 0.7 ug/mL). Regarding the antibacterial study, the M6 extract showed 16.55 ± 0.57 mm ZOI against E. coli and 15.54 ± 0.55 mm in the case of S. aureus, as compared to the standard ciprofloxacin, which showed 26.08 ± 0.73 mm, and penicillin, which showed 21.12 ± 0.81 mm ZOI. Mineral profiling was investigated by ICP-OES, which showed significant amounts of Mg and Fe in all extracts. Our findings tend to show that systematic harvesting and utilization of this vegetable crop could be recommended as an alternative nutritional therapy in the management of internal infections and diabetes.

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“…The genus of Lantana comprises ornamental plants with multipurpose uses such as the creation of flower beds, edgings and plant fences 1 which are characteristics of its noticeable position in landscape design 2 . Attractive flowering potted Lantana camara L. subsp.…”

Section: Introductionmentioning

confidence: 99%

Micronutrient Content in Relation to Specific Leaf Area, Light Regime and Drenched-Applied Paclobutrazol in Lantana Camara L.

2015

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Iron and manganese are essential microelements on plant growth but no information is known with regard to their content on Lantana camara L. subsp. camara (lantana) treated with drenched-applied paclobutrazol. Thus, the effects of drenched-applied paclobutrazol [0 (control), 40, and 80 mg l-1] on leaf iron and manganese contents of lantana plants were investigated testing two light regimes, resulted from the establishment of different shading levels, 0% (daily light quantity of 27.8 mol m-2 d-1) and 66% (9.4 mol m-2 d-1) in a glasshouse in Attica, Greece. Possible correlations between the studied minerals contents (iron and manganese) and specific leaf area were examined. Analysis of variance showed that iron and manganese contents were affected by shading level, paclobutrazol, their interaction and paclobutrazol, respectively. Iron content increased significantly after treatments with paclobutrazol, compared to control, at full light environment (0% shading). Leaf manganese content presented no significant increase with the increasing paclobutrazol concentrations at 0% and 66% shadings. No significant differences were noted (dispensing control plants) on iron and manganese contents, when examining plants which were treated with the same paclobutrazol concentration, between the studied light environments. From the linear correlation analysis, manganese content exhibited a significant negative correlation with specific leaf area which was not shown by the iron content. The results of the present study could contribute to establishing iron and manganese sufficiency ranges on L. camara, especially after treatments with different light environments and paclobutrazol

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Phenolic acid content, antioxidant properties, and antibacterial potential of flowers and fruits from selected Pakistani indigenous medicinal plants

Cited by 10 publications

References 24 publications

Phytochemicals, Health-Promoting Effects, and Enzyme Inhibition Traits of Phlomis stewartii Extracts

Phytochemicals, Health-Promoting Effects, and Enzyme Inhibition Traits of Phlomis stewartii Extracts

Evaluation of Anti-Infection and Anti-Diabetic Activities in Methanolic and n-Hexane Plant Extracts of Indigenously Cultivated Chenopodium album

Micronutrient Content in Relation to Specific Leaf Area, Light Regime and Drenched-Applied Paclobutrazol in Lantana Camara L.

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