Phenolic Compounds From Indonesian White Turmeric (Curcuma Zedoaria) Rhizomes

Rahayu, D. U. C.; Setyani, D. A.; Dianhar, Hanhan; Sugita, Purwantiningsih

doi:10.22159/ajpcr.2020.v13i7.38249

Cited by 6 publications

(2 citation statements)

References 27 publications

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“…This compound is known for its potent antioxidant properties. Therefore, the phenolic content of white turmeric, including curcuminoids, can majorly contribute to the antioxidant activity of white turmeric rhizomes [38], [39]. Blanching white turmeric powder has a higher content than fresh white turmeric.…”

Section: Resultsmentioning

confidence: 99%

Imunomodulator Properties of White Turmeric (Curcuma Mangga Val.) in Vivo

Pujimulyani,

Yulianto,

Indarto

et al. 2024

Preprint

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White turmeric contains bioactive compounds that have potential as immunomodulators. This research aims to assess the antioxidant properties and quantify the total phenolic content of white turmeric in vitro and test immunomodulatory properties in vivo. The study utilized a Completely Randomized Block Design (CRBD) with 2 treatment factors, namely the variation in parts of white turmeric rhizomes (main and tiller) and the variation in blanching time using the steam blanching method (0; 2.5; 5; 7.5; and 10 min). The analyses carried out were antioxidant activity of DPPH method (2,2 diphenyl-1-pickrylhidrazyl), and total phenolic content of white turmeric. Selected white turmeric powder based on in vitro test was analysed for immunomodulator (SOD (Superoxide Dismutase), IL-1 (Interleukin-1), IL-6 (Interleukin-6), IL-8 (Interleukin-8), IgE (Immunoglobulin E), IgG (Immunoglobulin G), dan IgM (Immunoglobulin M)). Selected white turmeric is the main rhizome with 5 min steam blanching. The analysis showed antioxidant activity of 81.46% RSA and total phenolic content of 6.08 mg EAG/g db. The results of in vivo studies showed that rats given white turmeric had an SOD value of 72.92% significantly better than rats given Na-CMC (Sodium Carboxymethyl Cellulose) and not significantly different from commercial supplements (stimuno). The IL-1 value of 0.40 pg/ml and IL-8 value of 48.53 pg/ml of rats given white kunir were significantly better than rats given Na-CMC and stimuno. The antibody values of IgE 74.02 ng/ml, IgG 18.20 ng/ml and IgM 2.97 ng/ml of rats treated with white turmeric were significantly better than those treated with Na-CMC and stimuno. The antibody values indicates that white turmeric has immunomodulatory effects.

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Section: Resultsmentioning

confidence: 99%

Imunomodulator Properties of White Turmeric (Curcuma Mangga Val.) in Vivo

Pujimulyani,

Yulianto,

Indarto

et al. 2024

Preprint

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“…Curcuma is rich in bioactive phytochemicals, with the major constituents consisting of phenolics (diarylheptanoids, diyrenphenate, and isoflavones), essential oils (monoterpenes, sesquiterpenes, diterpenes, and triterpenoids), steroids and alkaloids among others whereas, Curcuma essential oil is a blend of volatile terpenes comprising of monoterpenes, sesquiterpenes, diterpenes, and triterpenes. Phenolic compounds originating from natural resources have been interesting since they have demonstrated an interesting spectrum of biological activities such as antioxidant, anti-inflammatory, and anti-carcinogenic actions (Heleno et al 2015;Rahayu et al 2020).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical diversity and biological activities of Curcuma species from the East Coast of Peninsular Malaysia

YURASBE,

DIN,

PALANIVELOO

et al. 2023

Biodiversitas

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Abstract. Yurasbe NQ, Din NA, Palaniveloo K, Manikam S, Nagappan T. 2023. Phytochemical diversity and biological activities of Curcuma species from the East Coast of Peninsular Malaysia. Biodiversitas 24: 4243-4252. Zingiberaceae has been associated with traditional medicine for centuries. The genus Curcuma is traditionally famous and economically important for its therapeutic and nutritional values. Over 50 genera of 1600 species are recorded worldwide, with the highest concentration in the Malesian region, including Indonesia, Borneo, Thailand, Malaysia, Vietnam, Cambodia, Myanmar, and the Philippines. We investigated the methanolic crude extracts of Curcuma aeruginosa, Curcuma caesia, Curcuma longa, Curcuma xanthorrhiza, and Curcuma zedoaria from Terengganu for their phytochemicals, total phenolic content (TPC) using Folin-Ciocalteu colorimetric method, total flavonoid content (TFC) using aluminum chloride colorimetric method, antioxidant activity using the 2,2-diphenyl-1-picryl-hydrezyl (DPPH) radical scavenging activity and toxicity using brine shrimp lethality test (BSLT). Phytochemical screening revealed alkaloids, flavonoids, phenolics, saponins, tannins, triterpenoids, glycosides, lignins, and oils in all species investigated. Curcuma longa extract had the highest phenolic and flavonoid content with the value of 155.31±1.78 mg GAE/g and 151±8.35 mg quercetin/g, respectively as well as best antioxidative potential with IC50 value of 88.65±0.6 mg/mL, followed by C. zedoaria (98.61±5.23 mg/mL), C. aeruginosa (142.51±3.29 mg/mL), C. xanthorrhiza (150.01±0.63 mg/mL) and C. caesia (156.4±0.67 mg/mL). Curcuma caesia displays the lowest degree of toxicity compared to the other species, with the LC50 value of 11585 mg/mL) considered non-cytotoxic. Hence, the selected Curcuma species has potential therapeutic value to be developed into pharmaceutical due to its significant bioactive potentials and potent antioxidant capacity.

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