Phenolic Compounds From the Stems and Leaves of Berchemia lineata (L.) DC

Abstract

Eight new phenolic compounds, named bercheminols A-H (1–8), and eleven known analogues were isolated from the stems and leaves of Berchemia lineata (L.) DC. Their structures including the absolute configurations were elucidated by extensive spectroscopic analysis, chemical method, and quantum chemical calculations. Compound 1 possesses an unprecedented 3,4-dihydro-11H-benzo[b]pyrano[4,3-e] oxepin-11-one skeleton. The other new compounds belong to three structural types of natural products, including naphthopyrones (2–5), flavonoids (6–7), and bibenzyl (8). The α-glucosidase inhibitory activities of the isolated compounds were assayed. As a result, vittarin-B (9), rubrofusarin-6-O-β-D-glucopyranoside (11), quercetin (14), kaempferol (15), and dihydrokaempferol (17) showed moderate inhibitory activities against α-glucosidase with IC50 values of 22.5, 28.0, 36.5, 32.7, and 31.9 μM, respectively.

Chemical Constituents fromBerchemia polyphyllavar. Leioclada

“…Additionally, the remaining phenolic compounds were identified as floribundiquinone E ( 5 ), 16 quercetin ( 6 ), 21 kaempferol ( 7 ), 22 tricin ( 8 ), 23 isorhamnetin ( 9 ), 24 5,7,4′-trihydroxy-3,3′,5′-trimethoxyflavone ( 10 ), 25 naringenin ( 11 ), 26 5,7,3′,4′-tetrahydroxy-2-methoxy-3,4-flavandione-3-hydrate ( 12 ), 27 2,5-dimethyl-7-hydroxychromone ( 13 ), 28 2,5-dimethyl-7-methoxychromone ( 14 ), 29 vittarin-B ( 15 ), 30 3-methoxy-5-[2-(4-methoxyphenyl)ethyl]phenol ( 16 ), 31 (11 S )-diaprothin ( 17 ), 32 citreoisocoumarinol ( 18 ), 33 eleutherol ( 19 ), 34 bercheminol C ( 20 ), 5 rubrofusarin-6- O -α- l -rhamnosyl-(1 → 6)- O -β- d -glucopyranoside ( 21 ), 35 bercheminol A ( 22 ), 5 chrysophanol ( 23 ), 36 emodin ( 24 ), 37 and glucofrangulin A ( 25 ) 38 by comparisons of their spectroscopic data with reported values.…”

“…Previous studies have focused on phytochemical investigations of the stems and leaves of B. lineata , which have identified several new phenolic compounds including naphthopyrones, flavonoids, and bibenzyls. 5 However, there is limited research on the chemical constituents of B. polyphylla var. leioclada, which is another source of “Tiebaojin”.…”

Composition of Polygonatum zanlanscianense Pamp. Steam and Leaf Phenolic Extract and Its Protective Mechanism on t-BHP-Induced Oxidative Damage of HepG2 Cells

“…Phenolic compounds are receiving increasing attention in straw resources. Some studies [4][5][6][7][8] have revealed that the content of phenolic compounds in straw is higher than that in medicinal parts of plants, and that they have several important biological activities, including antioxidant, antitumor, neuroprotective, and antibacterial activities. The antioxidant biological activity exhibited by plant phenolic extracts can serve as an indirect antioxidant that activates the body's antioxidant mechanism by regulating the expression of intracellular antioxidant enzymes, thereby maintaining the body's redox homeostasis [9].…”

Detection of the Fungicide Dodine by means of Host‐Guest Complexation between Cucubit[10]uril and Acridine Orange

“…The approach involved a competitive interaction and the formation of a fluorescent turn-on system. [37][38][39][40][41] Herein, we investigate a related fluorescent turnon system based on Q [10] for the detection of DD, which utilizes the dye acridine orange (AO) as the initial guest, see scheme 1.…”