Phenolic compounds ofGeranium pusillum

Kobakhidze, K. B.; Alaniya, M. D.; Aneli, D. N.

doi:10.1007/bf02236305

Cited by 6 publications

(7 citation statements)

References 1 publication

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“…pl., namely different quercetin and kaempferol aglycones and glycoside derivatives. [34][35][36][37][38][39][40] Finally compound 11 ([M − H] − at m/z 563) was tentatively assigned as apigenin 2″-O-pentosyl-6-C-hexoside according to its pseudomolecular ion and fragmentation pattern. A compound with the same characteristics had been previously found by our group in Arenaria montana 41 and identified based on the fragmentation patterns described by Ferreres et al 42 and Ferreres et al 43 for O,C-glycosyl flavones.…”

Section: Analysis Of Phenolic Compounds In the Acetone Extractmentioning

confidence: 99%

Chemical characterization and bioactive properties of Geranium molle L.: from the plant to the most active extract and its phytochemicals

et al. 2016

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After a period of indifference, in which synthetic compounds were favored, there is an increasing interest in the study of the biological properties of plants and the active principles responsible for their therapeutic properties. Geranium molle L. has been used in the Portuguese folk medicine for the treatment of various ailments including cancer but, unlike many of the species from the Geranium genus, its phytochemical characterization and biological activity are virtually unexplored. In this study a G. molle sample from Trás-os-Montes, north-eastern Portugal, was chemically characterized regarding nutritional value, free sugars, organic acids, fatty acids and tocopherols, and several aqueous (decoction, infusion) and organic (n-hexane, dichloromethane, ethyl acetate, acetone, methanol) extracts of the plant were assessed for their bioactive properties. The antioxidant activity was evaluated by means of the free radicals scavenging activity, reducing power and inhibition of lipid peroxidation. The cytotoxicity of the different extracts was assessed in vitro against several human cancer cell lines (breast, lung, cervical and hepatocellular carcinomas) and, additionally, their hepatotoxicity was evaluated using a porcine liver primary cell culture. G. molle was shown to be rich in carbohydrates and proteins, providing tocopherols and essential fatty acids. Amongst the various extracts, the acetone extract was found to have the highest content of phenolic compounds (mainly ellagitannins, but also some flavone and flavonol glycosides) as well as the highest antioxidant and cytotoxic activities. To the best of our knowledge, this is the first report on the chemical composition and bioactive properties of G. molle.

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Section: Analysis Of Phenolic Compounds In the Acetone Extractmentioning

confidence: 99%

Chemical characterization and bioactive properties of Geranium molle L.: from the plant to the most active extract and its phytochemicals

et al. 2016

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“…Recently researches show that this kind of plant has a variety of biomedical activities such as antioxidant activity, anti-inflammatory activity, use against diarrhea, ulcer healing, reducing blood sugar, and prevention and treatment of diabetes complications [ 8 – 15 ]. The main components of the species include polyphenols, flavonoids, organic acid, and terpenoids [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Optimization of Extraction Process for Antidiabetic and Antioxidant Activities of Kursi Wufarikun Ziyabit Using Response Surface Methodology and Quantitative Analysis of Main Components

Edirs

Turak

Numonov

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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By using extraction yield, total polyphenolic content, antidiabetic activities (PTP-1B and α-glycosidase), and antioxidant activity (ABTS and DPPH) as indicated markers, the extraction conditions of the prescription Kursi Wufarikun Ziyabit (KWZ) were optimized by response surface methodology (RSM). Independent variables were ethanol concentration, extraction temperature, solid-to-solvent ratio, and extraction time. The result of RSM analysis showed that the four variables investigated have a significant effect (p < 0.05) for Y1, Y2, Y3, Y4, and Y5 with R2 value of 0.9120, 0.9793, 0.9076, 0.9125, and 0.9709, respectively. Optimal conditions for the highest extraction yield of 39.28%, PTP-1B inhibition rate of 86.21%, α-glycosidase enzymes inhibition rate of 96.56%, and ABTS inhibition rate of 77.38% were derived at ethanol concentration 50.11%, extraction temperature 72.06°C, solid-to-solvent ratio 1 : 22.73 g/mL, and extraction time 2.93 h. On the basis of total polyphenol content of 48.44% in this optimal condition, the quantitative analysis of effective part of KWZ was characterized via UPLC method, 12 main components were identified by standard compounds, and all of them have shown good regression within the test ranges and the total content of them was 11.18%.

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“…32 Heating EA leads to the formation of 2,2',3,3',4,4'biphenylhexol (BH, IUPAC: 4-(2,3,4-trihydroxyphenyl) benzene-1,2,3-triol), a polyphenol that resembles two PG units connected by a C-C bond, according to literature. 32,34,35 EA melts and decomposes at 350 C-360 C. 36,37 EA samples were provided in powder form by the Sigma-Aldrich company (purity ≥ 95%, product number: E2250). ) is a polyphenol and a representative for the class of gallotannins, consisting of a central glucose ring that is connected to five m-digallic acid (m-DGA) units via esterification (compare Figure S2d).…”

Section: Ellagic Acidmentioning

confidence: 99%

A Raman spectroscopic study of the pyrolysis of lactose and tannins

Brehm

Kraus

Himcinschi

et al. 2022

J Raman Spectroscopy

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Lactose and tannin are eco‐friendly alternatives to commonly used binders for carbon‐bonded alumina filters that are applied in steel melt filtration. The investigation of binder pyrolysis is a contribution to understand the production process of these filters. In this work, lactose and the tannins gallic acid, ellagic acid, and tannic acid were investigated by Raman spectroscopy. The tannins were measured in situ in an argon‐filled heating chamber. The transformation of the tannin molecules to a system of amorphous disordered carbon could be observed in the Raman spectra. In addition, the condensed pyrolysis products of the tannins were measured and identified. The Raman spectra were supported by peak positions calculated with density functional theory.

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Phenolic compounds ofGeranium pusillum

Cited by 6 publications

References 1 publication

Chemical characterization and bioactive properties of Geranium molle L.: from the plant to the most active extract and its phytochemicals

Chemical characterization and bioactive properties of Geranium molle L.: from the plant to the most active extract and its phytochemicals

Optimization of Extraction Process for Antidiabetic and Antioxidant Activities of Kursi Wufarikun Ziyabit Using Response Surface Methodology and Quantitative Analysis of Main Components

A Raman spectroscopic study of the pyrolysis of lactose and tannins

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