Phenolic profiles, antioxidant, antimicrobial, and DNA damage inhibitory activities of chestnut honeys from Black Sea Region of Turkey

Abstract

Honey is the product of beekeeping that has great market potential thanks to valuable nutritional and medicinal qualities. Black Sea Region coast of Turkey is suitable for production of chestnut production so chestnut-based honeys are highly produced in this region. To prove the beneficial therapeutic properties, 49 chestnut (Castania sativa Mill.) honey samples from the cities of Black Sea Region were investigated in terms of colors, total phenolic and flavonoid contents, antioxidant activities, antimicrobial potentials, phenolics, and effects on hydroxyl radical-induced DNA breaks in the non-site-specific system. The amount of flavonoid was found to be limited in chestnut honey samples compared to the phenolic acids. A wide variation was observed in the amounts of total antioxidant activities of honey samples. It was displayed that most of the tested honey samples had the ability to repair the DNA breaks created by hydroxyl radicals. Practical applicationsAs the chestnut honey (CH) is one of the most popular and valued honey around the world, the objective of this study was to reveal the potential of the Black Sea Region where CH production is being carried out effectively. Actually, CH samples investigated in this study had superior properties in terms of the parameters examined when compared with the results of similar studies.Antioxidant and antimicrobial activities of the CH samples at effective levels could be attributed to the presence of phenolic substances at a significant level. The high phenolic contents of the samples are predicted to contribute to the ability to resist DNA damage. With all these determined features, CHs can be useful in various applications such as medicine, cosmetics, and food. In this way, CH production in this region contribute to both the region's and the country's economy.

The antioxidant properties of the chestnut bee pollen extract and its preventive action against oxidatively induced damage in DNA bases

“…In this method, the ferric ion (Fe 3+ ) was reduced to ferrous ion (Fe 2+ ) by antioxidant compounds, and the blue‐colored ferrous complex was produced at the end of the reaction (Habib, Al Meqbali, Kamal, Souka, & Ibrahim, ). The antioxidant capacity of CBPE obtained by the FRAP method was threefold larger than the antioxidant capacity values of 49 chestnut honey samples that were extracted with water and methanol (Ayvaz et al, ). Due to the different environmental conditions, locality of the sample, and extraction methods, the antioxidant properties can be changed from one sample to another.…”

“…The main ROS compounds have been responsible for the formation of oxidative damage by attacking macromolecules, such as proteins and DNA. It is known that DNA oxidation is a cause of cancer, Alzheimer's disease, aging, and other genetic diseases (Ayvaz, Ömür, Ertürk, & Kabakçi, ). The investigation of the detection and prevention of DNA damage threatening human health has recently gained importance.…”

“…Bee pollen is a nutritional supplement that is important for health because of the medical properties of the honey bee. Researchers have shown that bee pollen contains sugar, amino acids, carbohydrates, proteins, vitamins, lipids, hormones, enzymes, and phenolic compounds (Ayvaz et al, ; Hegazi, ; Ulusoy & Kolayli, ). Natural bee pollen is commonly used for diseases, such as anemia, premature aging, ulcers, colds, and flu, and is also used in cosmetic and dietary products.…”

Determination of Antibacterial and DNA Damage Inhibitory Activities of Propolis Extract from Izmir of Turkey

“…Another form is formed III, which is a linear form and this form arises between form I and forms II. Plasmid analysis investigates the transformation of supercoiled plasmid DNA of radicals into linear or circular forms [21,22].…”

Comparison of the Antioxidant Activities and Phenolic Content of Five Lonicera Flowers by HPLC-DAD/MS-DPPH and Chemometrics

“…Epidemiological studies strongly showed antioxidant protection effects against various diseases or illness relevant to oxidative stress, such as aging, cardiovascular diseases, cancer, stoke, diabetes, Alzheimer's disease, hypertension, and inflammation [1][2][3][4][5]. Various antioxidants from natural products are excellent candidates, e.g., phenolic acids, tannins, lignans, and flavonoids) [6][7][8][9][10].…”